Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   OO773_RS01590 Genome accession   NZ_AP026769
Coordinates   269849..272284 (+) Length   811 a.a.
NCBI ID   WP_034375719.1    Uniprot ID   -
Organism   Helicobacter suis HS1     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 264849..277284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OO773_RS01560 (HSHS1_03090) - 265982..267157 (+) 1176 WP_006564106.1 site-specific DNA-methyltransferase -
  OO773_RS01565 (HSHS1_03100) - 267144..268010 (+) 867 WP_006564107.1 CfrBI family restriction endonuclease -
  OO773_RS01570 (HSHS1_03110) - 268180..268950 (+) 771 WP_034375711.1 hypothetical protein -
  OO773_RS01575 (HSHS1_03120) comB2 268983..269222 (+) 240 WP_050780158.1 TrbC/VirB2 family protein Machinery gene
  OO773_RS01580 (HSHS1_03130) comB3 269233..269496 (+) 264 WP_034375715.1 hypothetical protein Machinery gene
  OO773_RS01585 (HSHS1_03140) - 269516..269836 (+) 321 WP_034375717.1 hypothetical protein -
  OO773_RS01590 (HSHS1_03150) comB4 269849..272284 (+) 2436 WP_034375719.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  OO773_RS09790 (HSHS1_03160) - 272289..272498 (+) 210 WP_141556969.1 hypothetical protein -
  OO773_RS01600 (HSHS1_03170) - 272508..273599 (+) 1092 WP_050780156.1 VirB8/TrbF family protein -
  OO773_RS01605 (HSHS1_03180) - 273596..275125 (+) 1530 WP_006564108.1 TrbG/VirB9 family P-type conjugative transfer protein -
  OO773_RS01610 (HSHS1_03190) comB10 275115..276374 (+) 1260 WP_040499125.1 DNA type IV secretion system protein ComB10 Machinery gene

Sequence

Protein


Download         Length: 811 a.a.        Molecular weight: 93635.15 Da        Isoelectric Point: 8.2514

>NTDB_id=96881 OO773_RS01590 WP_034375719.1 269849..272284(+) (comB4) [Helicobacter suis HS1]
MLSDLFTFCKHKSIDYLAGLMPKTYSMVEENNILGIYDSQFLITKQENLVGLLELQGLSYLNLMQQDLEHYFNARQSALD
SIPLGVHLRIVAKRRKEQIKQNTQIDNPYARAIIAGFESKEIYDNRYYLVFESTTGTLKSFFEKKKLEMSTSIAESQDNQ
ERSKQKNITFINKHSMLKATMQRISHALKDFNPRELNSQEALRFYAEYINGFNIPLKPKMGILSDSYIASDVEFRKDYFL
INFKGKTTYQRFVGVKNYENQTITSVALSCLLHYACELDIIFSIEPLGIFESLHFLKVRKKFSFVNFVKEELDRYIDLVQ
ASRLSMQKIALNVLIRAESKESLDRHTEAVLNLLNNEGLVSKEETIGMIPSYFSFFPGRMDLNYRARYQTSSVMAALILF
EKNNRGFKANSWGDMPLSVFKNLDHSPYLFNFHNQEVQHKGVLAHNIARVNGHTMIIGATGAGKTTLMSYLMMSALKYPN
LDILALDRLNGLYSFTKYFGGVYNNDEEFYINPLTLEDSKENVEFLWSFYTYMLGIESTNKRDKELTEDQNAVRNAIGSM
YADHKKKSKQQEAYEPYTLEEFTNTFIKTQSEQIKGTLEPYLQNPIFNAREDCLEFKSRITTINMDSVINNQKDAGLLAY
YIFYKLIHRALHTNRGFFCFIDEFKSYAQNALMNDKINLIITQARKVNGVVALALQDIHQLDEVKNADSFIKNMGTLIFY
PQKNINTDKLKDQFGIKLSDLERHFLENTNVSSHQILIKNMNDSTSNVVDVSLAALGKYLPIFSSNASTMAHIKHLIKQY
PTSWREVFVHG

Nucleotide


Download         Length: 2436 bp        

>NTDB_id=96881 OO773_RS01590 WP_034375719.1 269849..272284(+) (comB4) [Helicobacter suis HS1]
ATGCTAAGTGATTTGTTTACATTTTGCAAACACAAGAGCATTGACTATCTAGCAGGCTTGATGCCTAAAACCTACTCTAT
GGTTGAGGAAAATAATATTCTAGGCATCTACGATTCCCAATTTTTAATCACCAAACAAGAGAATTTAGTAGGGTTGTTGG
AATTGCAGGGCTTGAGTTACTTGAATTTGATGCAACAGGATTTAGAACATTACTTTAATGCCCGCCAGAGTGCATTAGAT
AGTATCCCTCTAGGTGTGCATCTAAGAATTGTGGCTAAAAGAAGAAAAGAGCAAATCAAGCAGAATACACAGATAGATAA
TCCTTATGCTAGGGCTATCATTGCAGGATTTGAGAGCAAAGAGATTTATGATAACCGCTACTATCTTGTCTTTGAGAGCA
CAACAGGCACGCTTAAGAGCTTTTTTGAAAAGAAAAAGCTAGAGATGAGCACTTCTATAGCAGAGAGCCAAGATAATCAA
GAGCGCTCCAAGCAAAAAAACATCACCTTTATTAACAAGCACTCCATGCTCAAAGCAACCATGCAGAGAATAAGCCATGC
ACTCAAAGACTTCAACCCTAGAGAGCTTAACAGCCAAGAAGCCCTTAGATTTTATGCCGAATATATCAATGGCTTTAACA
TTCCTTTAAAACCTAAAATGGGCATTCTCAGCGATAGTTATATTGCTAGTGATGTAGAATTTAGAAAAGATTACTTCCTG
ATCAATTTTAAGGGCAAAACCACCTACCAACGCTTTGTAGGCGTGAAAAACTATGAAAACCAAACCATCACTTCTGTGGC
TCTCTCTTGCTTGTTACACTATGCATGTGAGCTAGACATTATCTTTTCTATAGAGCCTTTGGGCATTTTTGAGAGTTTGC
ATTTCTTAAAAGTACGCAAGAAATTTAGTTTTGTTAATTTTGTCAAAGAGGAGTTAGATAGATACATTGATCTGGTGCAA
GCTTCTAGACTCTCTATGCAAAAAATTGCCTTGAATGTGCTCATCAGAGCAGAAAGCAAAGAGAGTTTAGACAGACACAC
TGAGGCGGTTTTAAACTTGCTTAACAATGAAGGCTTGGTGAGCAAAGAGGAGACTATCGGGATGATACCCTCTTACTTTT
CTTTCTTTCCGGGTCGGATGGACTTAAACTATAGAGCTAGATACCAGACTTCTAGCGTGATGGCGGCCTTGATCTTGTTT
GAAAAGAATAACAGGGGCTTTAAAGCCAACTCTTGGGGGGATATGCCCTTGAGCGTGTTTAAAAACTTAGATCACTCCCC
TTATTTATTCAATTTCCACAACCAAGAAGTGCAACACAAGGGCGTGTTAGCCCACAATATTGCTAGAGTCAATGGACACA
CGATGATTATCGGAGCAACAGGAGCAGGCAAGACCACCTTGATGAGCTATTTGATGATGAGTGCTTTGAAATACCCAAAT
TTAGACATTTTAGCCCTAGATAGACTCAATGGCTTGTATTCCTTCACTAAATACTTTGGAGGGGTGTATAACAATGATGA
GGAGTTTTACATTAACCCTTTGACTTTAGAGGACTCTAAAGAAAATGTAGAGTTTTTGTGGAGCTTTTATACTTACATGC
TAGGCATTGAATCTACCAACAAAAGAGATAAAGAGCTCACAGAAGATCAAAATGCCGTGCGCAATGCTATTGGGAGTATG
TATGCAGACCACAAGAAAAAGAGCAAGCAGCAAGAAGCCTATGAGCCCTATACCTTAGAAGAGTTCACCAACACCTTTAT
TAAGACACAATCTGAACAAATCAAAGGCACTTTAGAGCCTTATTTGCAAAACCCCATTTTCAATGCCAGAGAGGATTGCC
TAGAGTTTAAAAGCCGCATCACCACCATTAATATGGATTCTGTGATCAACAACCAAAAAGACGCAGGGCTACTTGCTTAT
TACATTTTCTATAAGCTCATCCATAGAGCCTTGCACACCAATCGGGGCTTTTTTTGCTTCATTGATGAGTTTAAATCCTA
TGCGCAAAATGCGCTGATGAATGACAAGATTAATCTCATCATCACCCAAGCGCGCAAGGTCAATGGGGTGGTTGCTTTGG
CTTTGCAAGACATCCACCAGTTAGATGAAGTGAAAAATGCCGACAGCTTTATTAAAAATATGGGCACACTGATCTTCTAT
CCCCAAAAGAACATCAATACAGACAAGCTCAAAGACCAGTTTGGCATCAAACTTAGCGATTTAGAACGCCATTTCCTAGA
AAACACCAATGTTTCTAGCCACCAGATTTTAATTAAAAATATGAATGATAGCACTTCTAATGTGGTGGATGTGAGTTTGG
CTGCTCTAGGTAAGTATTTGCCTATCTTTAGTTCTAATGCCAGCACTATGGCACATATCAAGCATTTAATCAAACAATAC
CCAACTAGCTGGAGAGAAGTGTTTGTGCATGGGTAA

Domains

Predicted by InterProScan.

Helicase HerA, central domain (DUF87)

(450-629)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(187-385)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

51.673

99.507

0.514

Multiple sequence alignment