Detailed information NTG0961604

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ24_RS10340
• Genome accession: NZ_CP149807
• Coordinates: 2065053..2066096 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN123
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2060053..2071096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ24_RS10310 (UXQ24_10310)	-	2060471..2061727 (-)	1257	WP_001795438.1	aminopeptidase	-
UXQ24_RS10315 (UXQ24_10315)	-	2061730..2061930 (-)	201	WP_000180461.1	DUF1128 family protein	-
UXQ24_RS10320 (UXQ24_10320)	-	2062077..2062541 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ24_RS10325 (UXQ24_10325)	-	2062548..2062823 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ24_RS10330 (UXQ24_10330)	-	2063101..2064318 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ24_RS10335 (UXQ24_10335)	vraR	2064434..2065063 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXQ24_RS10340 (UXQ24_10340)	vraS	2065053..2066096 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ24_RS10345 (UXQ24_10345)	liaF	2066093..2066794 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ24_RS10350 (UXQ24_10350)	-	2066809..2067195 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ24_RS10355 (UXQ24_10355)	map	2067412..2068170 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ24_RS10360 (UXQ24_10360)	-	2068689..2069675 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXQ24_RS10365 (UXQ24_10365)	-	2070165..2070578 (-)	414	WP_001549145.1	hypothetical protein	-
UXQ24_RS10370 (UXQ24_10370)	-	2070607..2070717 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=961604 UXQ24_RS10340 WP_001017131.1 2065053..2066096(-) (vraS) [Staphylococcus aureus strain BSN123]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=961604 UXQ24_RS10340 WP_001017131.1 2065053..2066096(-) (vraS) [Staphylococcus aureus strain BSN123]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1