NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	V8946_RS24325	Genome accession	NZ_CP146591
Coordinates	4768950..4770074 (+)	Length	374 a.a.
NCBI ID	WP_213848255.1	Uniprot ID	-
Organism	Escherichia coli strain A1.S1.65
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 4763950..4775074

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V8946_RS24300 (V8946_24295)	mscL	4764067..4764480 (-)	414	WP_000022450.1	large-conductance mechanosensitive channel protein MscL	-
V8946_RS24305 (V8946_24300)	trkA	4764610..4765986 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
V8946_RS24310 (V8946_24305)	rsmB	4766008..4767297 (-)	1290	WP_000744773.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
V8946_RS24315 (V8946_24310)	fmt	4767349..4768296 (-)	948	WP_000004425.1	methionyl-tRNA formyltransferase	-
V8946_RS24320 (V8946_24315)	def	4768311..4768820 (-)	510	WP_000114984.1	peptide deformylase	-
V8946_RS24325 (V8946_24320)	dprA	4768950..4770074 (+)	1125	WP_213848255.1	DNA-protecting protein DprA	Machinery gene
V8946_RS24330 (V8946_24325)	smg	4770046..4770519 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
V8946_RS24335 (V8946_24330)	yrdD	4770548..4771090 (+)	543	WP_001312137.1	type I DNA topoisomerase	-
V8946_RS24340 (V8946_24335)	tsaC	4771095..4771666 (+)	572	Protein_4508	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
V8946_RS24345 (V8946_24340)	aroE	4771671..4772489 (+)	819	WP_000451249.1	shikimate dehydrogenase	-
V8946_RS24350 (V8946_24345)	yrdB	4772486..4772743 (+)	258	WP_001070563.1	DUF1488 domain-containing protein	-
V8946_RS24355 (V8946_24350)	yrdA	4772719..4773273 (-)	555	WP_001286206.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40900.82 Da Isoelectric Point: 6.0395

                                >NTDB_id=943227 V8946_RS24325 WP_213848255.1 4768950..4770074(+) (dprA) [Escherichia coli strain A1.S1.65]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGSHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=943227 V8946_RS24325 WP_213848255.1 4768950..4770074(+) (dprA) [Escherichia coli strain A1.S1.65]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT

TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGCCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGTCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATTGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.78	98.663	0.481
dprA	Vibrio cholerae strain A1552	49.677	82.888	0.412
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	44.242	88.235	0.39

Detailed information NTG0943227