Detailed information NTG0937199

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: V5G15_RS10375
• Genome accession: NZ_CP145090
• Coordinates: 1977328..1978515 (-)
• Length: 395 a.a.
• NCBI ID: WP_004466865.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO_A_2024
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1972328..1983515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G15_RS10345 (V5G15_10370)	-	1972656..1973405 (-)	750	Protein_2009	opacity family porin	-
V5G15_RS10350 (V5G15_10375)	-	1973355..1973501 (+)	147	WP_154236000.1	hypothetical protein	-
V5G15_RS10355 (V5G15_10380)	-	1973580..1974124 (-)	545	Protein_2011	IS1595 family transposase	-
V5G15_RS10360 (V5G15_10385)	-	1974114..1974242 (-)	129	Protein_2012	phosphomethylpyrimidine synthase ThiC	-
V5G15_RS10365 (V5G15_10390)	topA	1974463..1976769 (-)	2307	WP_057321724.1	type I DNA topoisomerase	-
V5G15_RS10370 (V5G15_10395)	-	1976841..1977302 (-)	462	WP_003690120.1	DUF494 domain-containing protein	-
V5G15_RS10375 (V5G15_10400)	dprA	1977328..1978515 (-)	1188	WP_004466865.1	DNA-processing protein DprA	Machinery gene
V5G15_RS10380 (V5G15_10405)	-	1978606..1979883 (-)	1278	WP_003690124.1	sigma-54 dependent transcriptional regulator	-
V5G15_RS10385 (V5G15_10410)	-	1979876..1981996 (-)	2121	WP_082284933.1	PAS domain-containing sensor histidine kinase	-
V5G15_RS10390 (V5G15_10415)	-	1981996..1982595 (-)	600	WP_003690290.1	DUF4390 domain-containing protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41877.93 Da
• Isoelectric Point: 6.2394

>NTDB_id=937199 V5G15_RS10375 WP_004466865.1 1977328..1978515(-) (dprA) [Neisseria gonorrhoeae strain WHO_A_2024]
MTEDERFAWLQLAFTPYIGAESFLLLMRSFGSAQNALSAPAEQVAPAVRHKHALEAWHNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPTVSGMASGIDT
AAHQGALEAEGGTVAVWGTGIDRIYPPANKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTPDTGRRTVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=937199 V5G15_RS10375 WP_004466865.1 1977328..1978515(-) (dprA) [Neisseria gonorrhoeae strain WHO_A_2024]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCAGTTTCGGCAGCGCGCAAAATGCCTTGTCCGCACCGGCGGAACAGGTTGCCCCGGCGGTGCGGCATAAGCACGCGC
TTGAGGCTTGGCACAATGCGGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCTACCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCGTCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GGCCAACAAAAACCTTGCTTATGAAATCGCCGAAAAAGGGCTGATTGTCAGCGAGTTCCCCATCGGCACGCGGCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCGTCATATTCTATAAATAAGGATACGCCCGACACGGGCCGCCGCACCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCCATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

• DprA winged helix domain (DprA_WH) (341-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	99.494	100	0.995
dprA	Neisseria gonorrhoeae strain FA1090	99.241	100	0.992
dprA	Neisseria meningitidis strain C311	89.421	100	0.899
dprA	Neisseria meningitidis MC58	89.421	100	0.899
dprA	Vibrio cholerae strain A1552	36.962	100	0.37