Detailed information NTG0936825

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: V5G04_RS10175
• Genome accession: NZ_CP145067
• Coordinates: 1943397..1944584 (+)
• Length: 395 a.a.
• NCBI ID: WP_047919128.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO_N_2024
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1938397..1949584

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G04_RS10160 (V5G04_10190)	-	1939317..1939916 (+)	600	WP_003690290.1	DUF4390 domain-containing protein	-
V5G04_RS10165 (V5G04_10195)	-	1939916..1942036 (+)	2121	WP_003690126.1	HAMP domain-containing histidine kinase	-
V5G04_RS10170 (V5G04_10200)	-	1942029..1943306 (+)	1278	WP_003690124.1	sigma-54 dependent transcriptional regulator	-
V5G04_RS10175 (V5G04_10205)	dprA	1943397..1944584 (+)	1188	WP_047919128.1	DNA-processing protein DprA	Machinery gene
V5G04_RS10180 (V5G04_10210)	-	1944610..1945071 (+)	462	WP_003690120.1	DUF494 domain-containing protein	-
V5G04_RS10185 (V5G04_10215)	topA	1945149..1947455 (+)	2307	WP_047951377.1	type I DNA topoisomerase	-
V5G04_RS10190 (V5G04_10220)	-	1947676..1947804 (+)	129	Protein_1975	phosphomethylpyrimidine synthase ThiC	-
V5G04_RS10195 (V5G04_10225)	-	1947794..1948338 (+)	545	Protein_1976	IS1595 family transposase	-
V5G04_RS10200 (V5G04_10230)	-	1948436..1948594 (+)	159	WP_332094903.1	hypothetical protein	-
V5G04_RS10205 (V5G04_10235)	-	1948522..1949289 (+)	768	Protein_1978	opacity family porin	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41861.93 Da
• Isoelectric Point: 6.2394

>NTDB_id=936825 V5G04_RS10175 WP_047919128.1 1943397..1944584(+) (dprA) [Neisseria gonorrhoeae strain WHO_N_2024]
MTEDERFAWLQLAFTPYIGAESFLLLMRSFGSAQNALSAPAEQVAPAVRHKHALEAWHNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPTVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPANKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=936825 V5G04_RS10175 WP_047919128.1 1943397..1944584(+) (dprA) [Neisseria gonorrhoeae strain WHO_N_2024]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCAGTTTCGGCAGCGCGCAAAATGCCTTGTCCGCACCGGCGGAACAGGTTGCCCCGGCGGTGCGGCATAAGCACGCGC
TTGAGGCTTGGCACAATGCAGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCTACCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GGCCAACAAAAACCTTGCCTATGAAATCGCCGAAAAAGGGCTGATTGTCAGCGAGTTCCCCATCGGCACGCGGCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAACCCCCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGAGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCGTCATATTCTATAAATAAGGATACGCCCGACACGGGCCGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

• DprA winged helix domain (DprA_WH) (341-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	99.494	100	0.995
dprA	Neisseria gonorrhoeae strain FA1090	99.241	100	0.992
dprA	Neisseria meningitidis strain C311	89.924	100	0.904
dprA	Neisseria meningitidis MC58	89.924	100	0.904
dprA	Vibrio cholerae strain A1552	37.28	100	0.375