Detailed information NTG0935861

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: V5G07_RS10500
• Genome accession: NZ_CP145015
• Coordinates: 2000194..2001381 (+)
• Length: 395 a.a.
• NCBI ID: WP_106178855.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO_Z_2024
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1995194..2006381

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G07_RS10485 (V5G07_10515)	-	1996114..1996713 (+)	600	WP_003690128.1	DUF4390 domain-containing protein	-
V5G07_RS10490 (V5G07_10520)	-	1996713..1998833 (+)	2121	WP_003694352.1	HAMP domain-containing histidine kinase	-
V5G07_RS10495 (V5G07_10525)	-	1998826..2000103 (+)	1278	WP_003690124.1	sigma-54 dependent transcriptional regulator	-
V5G07_RS10500 (V5G07_10530)	dprA	2000194..2001381 (+)	1188	WP_106178855.1	DNA-processing protein DprA	Machinery gene
V5G07_RS10505 (V5G07_10535)	-	2001407..2001868 (+)	462	WP_003690295.1	DUF494 domain-containing protein	-
V5G07_RS10510 (V5G07_10540)	topA	2001946..2004252 (+)	2307	WP_014580418.1	type I DNA topoisomerase	-
V5G07_RS10515 (V5G07_10545)	-	2004473..2004601 (+)	129	Protein_2039	phosphomethylpyrimidine synthase ThiC	-
V5G07_RS10520 (V5G07_10550)	-	2004591..2005135 (+)	545	Protein_2040	IS1595 family transposase	-
V5G07_RS10525 (V5G07_10555)	-	2005304..2006068 (+)	765	Protein_2041	opacity family porin	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41868.96 Da
• Isoelectric Point: 6.3096

>NTDB_id=935861 V5G07_RS10500 WP_106178855.1 2000194..2001381(+) (dprA) [Neisseria gonorrhoeae strain WHO_Z_2024]
MTEDERFAWLQLAFTPYIGAESFLLLMRSFGSAQNALSAPAEQVAPAVRHKHALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLIAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPTVSGMASGIDT
AAHQGALEAEGGTVAVWGTGIDRIYPSANKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=935861 V5G07_RS10500 WP_106178855.1 2000194..2001381(+) (dprA) [Neisseria gonorrhoeae strain WHO_Z_2024]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCAGTTTCGGCAGCGCGCAAAATGCCTTGTCCGCACCGGCGGAACAGGTTGCCCCGGCGGTGCGGCATAAGCACGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGATCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCTACCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCGTCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGTC
GGCCAACAAAAACCTTGCCTATGAAATCGCCGAAAAAGGGCTGATTGTCAGCGAGTTCCCCATCGGCACGCGGCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTCATGGCGGTGCCCGGTTCGATAGACAACCCCCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGAGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCGTCATATTCTATAAATAAGGATACGCCCGACACGGGCCGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

• DprA winged helix domain (DprA_WH) (341-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae strain FA1090	99.241	100	0.992
dprA	Neisseria gonorrhoeae MS11	98.987	100	0.99
dprA	Neisseria meningitidis strain C311	89.421	100	0.899
dprA	Neisseria meningitidis MC58	89.421	100	0.899
dprA	Vibrio cholerae strain A1552	37.531	100	0.377