Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   ACB340_RS05420 Genome accession   NZ_CP167005
Coordinates   1052600..1054591 (-) Length   663 a.a.
NCBI ID   WP_002989569.1    Uniprot ID   P0DH39
Organism   Streptococcus pyogenes strain Isolate 27     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1047600..1059591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB340_RS05395 (ACB340_05395) dltD 1047890..1049140 (-) 1251 WP_011017899.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -
  ACB340_RS05400 (ACB340_05400) dltC 1049133..1049372 (-) 240 WP_002984216.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  ACB340_RS05405 (ACB340_05405) dltB 1049390..1050646 (-) 1257 WP_002994626.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  ACB340_RS05410 (ACB340_05410) dltA 1050643..1052181 (-) 1539 WP_023079019.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  ACB340_RS05415 (ACB340_05415) - 1052193..1052336 (-) 144 WP_023079026.1 teichoic acid D-Ala incorporation-associated protein DltX -
  ACB340_RS05420 (ACB340_05420) uvrB 1052600..1054591 (-) 1992 WP_002989569.1 excinuclease ABC subunit UvrB Machinery gene
  ACB340_RS05425 (ACB340_05425) - 1054784..1056958 (+) 2175 WP_115224589.1 ABC transporter substrate-binding protein/permease -
  ACB340_RS05430 (ACB340_05430) - 1056958..1057698 (+) 741 WP_002984187.1 amino acid ABC transporter ATP-binding protein -
  ACB340_RS05435 (ACB340_05435) - 1057846..1057998 (-) 153 WP_023079022.1 hypothetical protein -
  ACB340_RS05440 (ACB340_05440) - 1057995..1059331 (-) 1337 Protein_1025 PTS sugar transporter subunit IIC -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 75664.72 Da        Isoelectric Point: 4.6420

>NTDB_id=930072 ACB340_RS05420 WP_002989569.1 1052600..1054591(-) (uvrB) [Streptococcus pyogenes strain Isolate 27]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=930072 ACB340_RS05420 WP_002989569.1 1052600..1054591(-) (uvrB) [Streptococcus pyogenes strain Isolate 27]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTGTCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTAGAATTTTTTGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGATCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGCCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAATCAGCGCGTAGCGCGTGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGGACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGAGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTCCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB interaction domain (UvrB_inter)

(164-254)

Helicase conserved C-terminal domain (Helicase_C)

(443-548)

Type III restriction enzyme, res subunit (ResIII)

(17-142)

UvrB/uvrC motif (UVR)

(627-660)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DH39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

85.068

100

0.851
  uvrB Streptococcus pneumoniae D39

85.068

100

0.851
  uvrB Streptococcus pneumoniae TIGR4

84.917

100

0.849