Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   ACB354_RS05510 Genome accession   NZ_CP167004
Coordinates   1018362..1019150 (+) Length   262 a.a.
NCBI ID   WP_011184611.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 28     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1013362..1024150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB354_RS05440 (ACB354_05440) - 1013590..1014057 (-) 468 WP_021340160.1 hypothetical protein -
  ACB354_RS05445 (ACB354_05445) - 1014054..1014338 (-) 285 WP_021340157.1 hypothetical protein -
  ACB354_RS05450 (ACB354_05450) - 1014335..1014529 (-) 195 WP_002984315.1 hypothetical protein -
  ACB354_RS05455 (ACB354_05455) - 1014529..1014858 (-) 330 WP_002984312.1 hypothetical protein -
  ACB354_RS05460 (ACB354_05460) - 1014939..1015076 (-) 138 WP_011184604.1 hypothetical protein -
  ACB354_RS05465 (ACB354_05465) - 1015073..1015369 (-) 297 WP_011184605.1 MerR family transcriptional regulator -
  ACB354_RS05470 (ACB354_05470) - 1015446..1015622 (-) 177 WP_011184606.1 helix-turn-helix domain-containing protein -
  ACB354_RS05475 (ACB354_05475) - 1015765..1015986 (+) 222 WP_002992762.1 hypothetical protein -
  ACB354_RS05480 (ACB354_05480) - 1015944..1016285 (-) 342 WP_011184607.1 hypothetical protein -
  ACB354_RS05485 (ACB354_05485) - 1016452..1016697 (-) 246 WP_002984287.1 hypothetical protein -
  ACB354_RS05490 (ACB354_05490) - 1016709..1016948 (-) 240 WP_021340169.1 helix-turn-helix transcriptional regulator -
  ACB354_RS05495 (ACB354_05495) - 1017046..1017729 (+) 684 WP_011017887.1 DUF4145 domain-containing protein -
  ACB354_RS05500 (ACB354_05500) - 1017856..1018014 (-) 159 WP_011184610.1 hypothetical protein -
  ACB354_RS05505 (ACB354_05505) - 1018073..1018240 (+) 168 WP_021340161.1 hypothetical protein -
  ACB354_RS05510 (ACB354_05510) irvR 1018362..1019150 (+) 789 WP_011184611.1 S24 family peptidase Regulator
  ACB354_RS05515 (ACB354_05515) - 1019160..1019465 (+) 306 WP_011106738.1 membrane protein -
  ACB354_RS05520 (ACB354_05520) - 1019585..1020673 (+) 1089 WP_011017891.1 site-specific integrase -
  ACB354_RS05525 (ACB354_05525) - 1021035..1021655 (+) 621 WP_011184613.1 DUF3862 domain-containing protein -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 30022.16 Da        Isoelectric Point: 8.1141

>NTDB_id=929984 ACB354_RS05510 WP_011184611.1 1018362..1019150(+) (irvR) [Streptococcus pyogenes strain Isolate 28]
MARGRGKLTPQDEEYKKIISAKINSLLLENNLKQGHLADALEIPRSSFNEYVKGNSLPNPGNVQKIADYFGLMKSDIDPR
FAPRKKNHELKIPTSPLVKKITTTVVELNVPRKQKVLDFATEQLKEQKNKITSIEKKLYEYKVYEKLSAGTGYGYFGDGN
YDTVFYDEELDYDFASWVFGDSMEPTYVNGEVVLIKQTGFDYEGGIYAVEWDGQTYIKKVYREKDGLRLVSLNKKYNDKF
APFSEGPRIIGEIVGNFMPKEY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=929984 ACB354_RS05510 WP_011184611.1 1018362..1019150(+) (irvR) [Streptococcus pyogenes strain Isolate 28]
ATGGCAAGAGGACGAGGGAAGTTAACACCTCAAGACGAGGAATACAAAAAGATAATTTCTGCTAAAATTAACAGTTTATT
GCTAGAAAACAATTTAAAACAAGGACATTTAGCTGATGCATTGGAAATTCCACGAAGTAGTTTTAATGAATATGTCAAAG
GAAATTCCTTACCTAATCCTGGTAACGTTCAAAAGATAGCTGATTATTTCGGGTTAATGAAGTCTGATATAGATCCTAGA
TTTGCACCTCGTAAGAAAAATCACGAACTCAAAATCCCTACTTCTCCACTCGTCAAAAAAATAACCACAACAGTTGTAGA
ATTAAATGTTCCTCGTAAACAAAAAGTTTTAGACTTTGCAACAGAACAATTGAAAGAGCAAAAAAACAAAATTACTTCGA
TAGAGAAAAAACTATATGAATACAAAGTCTATGAGAAACTTTCCGCAGGTACAGGTTATGGGTATTTTGGTGATGGGAAC
TATGATACTGTTTTTTACGACGAAGAATTAGATTACGATTTTGCCTCTTGGGTTTTTGGTGATTCTATGGAACCAACTTA
TGTGAATGGTGAGGTTGTGCTTATAAAACAAACTGGCTTTGATTATGAAGGTGGCATCTATGCCGTAGAGTGGGACGGAC
AAACCTATATTAAGAAAGTTTACAGAGAAAAGGATGGCTTGCGCCTTGTGTCCTTAAATAAAAAATACAATGACAAGTTT
GCTCCTTTTAGTGAAGGCCCTCGTATAATAGGGGAAATTGTCGGTAACTTTATGCCTAAAGAGTACTGA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(168-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

38.158

100

0.443