Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   AB2U05_RS18560 Genome accession   NZ_CP163445
Coordinates   4327250..4328308 (+) Length   352 a.a.
NCBI ID   WP_045704365.1    Uniprot ID   A0A0F2T7C7
Organism   Streptomyces sp. Y1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4322250..4333308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB2U05_RS18550 (AB2U05_18550) - 4323439..4325343 (-) 1905 WP_369183787.1 hypothetical protein -
  AB2U05_RS18555 (AB2U05_18555) radA 4325537..4327048 (+) 1512 WP_369183788.1 DNA repair protein RadA Machinery gene
  AB2U05_RS18560 (AB2U05_18560) disA 4327250..4328308 (+) 1059 WP_045704365.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  AB2U05_RS18565 (AB2U05_18565) - 4328399..4329217 (-) 819 WP_369183789.1 hypothetical protein -
  AB2U05_RS18570 (AB2U05_18570) - 4329432..4330349 (+) 918 WP_045704356.1 A/G-specific adenine glycosylase -
  AB2U05_RS18575 (AB2U05_18575) - 4330427..4332025 (-) 1599 WP_045704354.1 MDR family MFS transporter -
  AB2U05_RS18580 (AB2U05_18580) - 4332274..4332957 (+) 684 WP_052706580.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38436.20 Da        Isoelectric Point: 5.5407

>NTDB_id=925704 AB2U05_RS18560 WP_045704365.1 4327250..4328308(+) (disA) [Streptomyces sp. Y1]
MRASLTAIAPGTALRDGLERVLRANTGGLIVLGFDKTVESICTGGFVLDVEFTATRLRELCKLDGAVVLDKDITKIVRAG
VHLMPDSTIPTDETGTRHRTAERVNRQTGYPVVAVSHSMRLIAMYVNGTRRVLEDSTTVLSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVTAVAQRLEMVRLIATEIAGYVLELGIDGRLLSLQLDELIAGVEPERELVARDYFPERAAKKG
RTVTEVLADLEALTHAELLDLQTVAKALGYSGTPESLDSAVSPRGYRLLAKIPRLPNTVIERLVEHFGGLQKLLAASIDD
LQTVEGVGETRARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=925704 AB2U05_RS18560 WP_045704365.1 4327250..4328308(+) (disA) [Streptomyces sp. Y1]
CTGCGGGCCTCCCTCACCGCCATCGCGCCCGGCACCGCCCTGCGTGACGGTCTGGAACGGGTCCTGCGGGCCAACACCGG
TGGCCTGATCGTGCTGGGCTTCGACAAGACCGTCGAGTCCATCTGCACCGGCGGCTTCGTCCTGGACGTCGAGTTCACCG
CGACCCGGCTGCGCGAGCTGTGCAAGCTGGACGGCGCGGTGGTGCTCGACAAGGACATCACCAAGATCGTCCGGGCCGGC
GTCCACCTGATGCCGGACTCCACCATCCCCACCGACGAGACCGGCACCCGCCACCGCACCGCCGAGCGGGTCAACCGGCA
GACCGGCTACCCGGTCGTCGCGGTCTCGCACTCGATGCGCCTGATCGCCATGTACGTCAACGGCACCCGCCGGGTCCTGG
AGGACTCGACCACCGTGCTGTCCCGCGCCAACCAGGCGCTGGCCACCCTGGAGCGCTACAAGCTGCGCCTGGACGAGGTG
GCCGGCACGCTCTCCGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCACGGCCGTCGCCCAGCGCCTGGAGAT
GGTCCGGCTGATCGCCACCGAGATCGCCGGCTACGTGCTGGAGCTCGGCATCGACGGCCGCCTCCTCTCGCTCCAGCTGG
ACGAGCTGATCGCGGGCGTCGAGCCGGAGCGCGAGCTGGTCGCCCGGGACTACTTCCCGGAGCGGGCCGCCAAGAAGGGC
CGGACGGTCACCGAGGTGCTGGCCGACCTGGAGGCGCTCACCCACGCCGAGCTGCTGGACCTCCAGACGGTCGCCAAGGC
GCTCGGCTACTCGGGCACGCCGGAGTCGCTGGACTCCGCCGTCTCGCCGCGCGGCTACCGGCTGCTGGCGAAGATCCCGC
GTCTGCCCAACACGGTCATAGAGCGCCTGGTCGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCGGCCAGCATCGACGAC
CTGCAGACGGTCGAGGGCGTCGGCGAGACCCGGGCCCGCTCGGTCCGCGAGGGCCTGTCCCGCCTTGCCGAATCGTCCAT
CCTGGAGCGCTACGTCTGA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)

Helix-hairpin-helix motif (HHH_2)

(301-337)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2T7C7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

46.243

98.295

0.455