Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   VFH86_RS00175 Genome accession   NZ_CP142014
Coordinates   38642..39757 (+) Length   371 a.a.
NCBI ID   WP_345657886.1    Uniprot ID   -
Organism   Vibrio cholerae strain LK-18     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 33642..44757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VFH86_RS00155 (VFH86_00155) rsmB 34565..35845 (-) 1281 WP_114743424.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  VFH86_RS00160 (VFH86_00160) fmt 35901..36848 (-) 948 WP_019829590.1 methionyl-tRNA formyltransferase -
  VFH86_RS00165 (VFH86_00165) def 36866..37375 (-) 510 WP_000115010.1 peptide deformylase -
  VFH86_RS00170 (VFH86_00170) - 37515..38642 (+) 1128 WP_162805576.1 LysM peptidoglycan-binding domain-containing protein -
  VFH86_RS00175 (VFH86_00175) dprA 38642..39757 (+) 1116 WP_345657886.1 DNA-processing protein DprA Machinery gene
  VFH86_RS00180 (VFH86_00180) - 39760..40236 (+) 477 WP_000979769.1 DUF494 family protein -
  VFH86_RS00185 (VFH86_00185) - 40250..40816 (+) 567 WP_000087520.1 type I DNA topoisomerase -
  VFH86_RS00190 (VFH86_00190) - 40889..42022 (-) 1134 WP_345657890.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  VFH86_RS00195 (VFH86_00195) purE 42026..42511 (-) 486 WP_000215768.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  VFH86_RS00200 (VFH86_00200) - 42678..43235 (+) 558 WP_033839258.1 L-threonylcarbamoyladenylate synthase -
  VFH86_RS00205 (VFH86_00205) hemF 43254..44171 (+) 918 WP_000443975.1 oxygen-dependent coproporphyrinogen oxidase -

Sequence

Protein


Download         Length: 371 a.a.        Molecular weight: 40025.10 Da        Isoelectric Point: 7.4547

>NTDB_id=920916 VFH86_RS00175 WP_345657886.1 38642..39757(+) (dprA) [Vibrio cholerae strain LK-18]
MKEQDLAAWLALCFTPKLGSKTISHLLATRLPAQLQSFTPKQWLACGLKPEQLVFLTTQAAKQAELCLQWRSAANNRYIV
TPHCPLYPRLLKEISSSPPVLFIEGIWEAVHYPAVAIVGSRNASVDGRQIARQFATELAQSGLVVTSGLALGIDGYAHDG
ALQAQGQTVAVLGSGLAQVYPKQHQGLAERIIAQGALVSEFAPHTPPKADHFPRRNRIISGLSLGVVVVEAAEKSGSLIT
ARYAAEQGREVFVVPGSIFNAASQGSNQLIRQGACLVQSVQQIHQELKNALTWSLSEQVPYQATLFSAVQGDEELPFPEL
LANVGIEATPIDILASRTQIPVQDIMMQLLELELLGHVVAVPGGYIRKGRG

Nucleotide


Download         Length: 1116 bp        

>NTDB_id=920916 VFH86_RS00175 WP_345657886.1 38642..39757(+) (dprA) [Vibrio cholerae strain LK-18]
ATGAAAGAGCAGGATTTAGCGGCATGGTTGGCGCTCTGTTTTACTCCTAAACTAGGCAGCAAAACCATTTCTCACCTGCT
TGCGACCCGTTTGCCAGCCCAGTTGCAAAGTTTTACGCCTAAGCAATGGTTGGCCTGCGGGCTTAAGCCCGAACAACTGG
TGTTTTTAACCACTCAAGCGGCTAAGCAAGCCGAGCTGTGTTTGCAATGGCGATCAGCAGCCAATAACCGCTATATCGTC
ACTCCTCATTGCCCGCTTTACCCTCGTTTATTGAAAGAGATTAGCTCATCGCCTCCCGTCCTGTTTATTGAAGGAATATG
GGAAGCGGTGCATTACCCCGCGGTAGCTATCGTGGGTAGCCGCAATGCCAGTGTTGATGGGCGGCAGATCGCTCGCCAAT
TTGCCACTGAGCTCGCGCAGTCGGGTTTAGTGGTCACCAGTGGTTTAGCGCTTGGTATAGACGGCTATGCGCACGATGGC
GCTTTGCAAGCACAAGGGCAAACCGTGGCAGTATTAGGCTCAGGGCTGGCGCAGGTTTACCCCAAACAGCATCAAGGGTT
AGCGGAGCGAATCATCGCCCAAGGGGCCTTGGTTTCTGAGTTTGCCCCTCACACACCTCCTAAAGCCGATCACTTTCCGC
GCCGTAACCGAATTATCAGCGGCTTATCGCTCGGTGTTGTGGTGGTAGAAGCTGCGGAGAAAAGTGGCTCACTCATCACT
GCACGCTACGCCGCTGAGCAAGGGCGTGAGGTCTTTGTGGTTCCCGGCTCGATTTTTAATGCCGCCAGCCAAGGTAGCAA
TCAATTGATTCGTCAAGGCGCTTGTTTGGTGCAAAGTGTGCAACAAATTCATCAAGAGCTCAAAAATGCGCTGACTTGGT
CACTCTCTGAACAAGTTCCTTATCAAGCAACACTTTTTTCTGCTGTACAGGGCGATGAAGAATTGCCATTTCCCGAGCTG
TTAGCTAACGTAGGAATAGAAGCTACACCTATTGATATTCTCGCAAGCCGGACCCAGATACCGGTGCAAGATATCATGAT
GCAGCTCTTGGAGCTTGAGCTCCTTGGGCATGTGGTTGCAGTACCTGGTGGCTATATTAGAAAGGGGAGAGGCTAG

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(77-278)

DprA winged helix domain (DprA_WH)

(319-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio cholerae strain A1552

98.652

100

0.987
  dprA Vibrio campbellii strain DS40M4

58.311

98.922

0.577
  dprA Glaesserella parasuis strain SC1401

43.617

100

0.442
  dprA Legionella pneumophila strain ERS1305867

43.316

100

0.437
  dprA Neisseria meningitidis strain C311

38.095

100

0.41
  dprA Neisseria meningitidis MC58

38.095

100

0.41
  dprA Neisseria gonorrhoeae strain FA1090

37.28

100

0.399
  dprA Neisseria gonorrhoeae MS11

36.456

100

0.388
  dprA Acinetobacter baumannii D1279779

43.202

89.218

0.385
  dprA Acinetobacter baumannii strain A118

42.9

89.218

0.383
  dprA Acinetobacter baylyi ADP1

41.742

89.757

0.375
  dprA Haemophilus influenzae Rd KW20

48.746

75.202

0.367