Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   VF946_RS11605 Genome accession   NZ_CP141824
Coordinates   2319970..2321166 (+) Length   398 a.a.
NCBI ID   WP_009911075.1    Uniprot ID   G7SHV4
Organism   Streptococcus suis strain HB18     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2314970..2326166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS11575 - 2315629..2318208 (+) 2580 WP_012028056.1 YfhO family protein -
  VF946_RS11595 - 2318609..2319292 (-) 684 WP_012775416.1 YoaK family protein -
  VF946_RS11600 rlmH 2319317..2319796 (-) 480 WP_012028058.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  VF946_RS11605 htrA 2319970..2321166 (+) 1197 WP_009911075.1 S1C family serine protease Regulator
  VF946_RS11610 spo0J 2321227..2321991 (+) 765 WP_014638879.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 41818.83 Da        Isoelectric Point: 4.6655

>NTDB_id=919781 VF946_RS11605 WP_009911075.1 2319970..2321166(+) (htrA) [Streptococcus suis strain HB18]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPRVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=919781 VF946_RS11605 WP_009911075.1 2319970..2321166(+) (htrA) [Streptococcus suis strain HB18]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAGCCACGGGTTCAACAAGCAAATTCTGCCATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCTACTACAAAGGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCCGTTGCTGGGGAGGGATCTGGTGTTAT
CTACAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCTGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(293-389)

Trypsin-like peptidase domain (Trypsin_2)

(103-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SHV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

59.446

99.749

0.593
  htrA Streptococcus gordonii str. Challis substr. CH1

59.494

99.246

0.59
  htrA Streptococcus pneumoniae D39

57.252

98.744

0.565
  htrA Streptococcus pneumoniae TIGR4

57.252

98.744

0.565
  htrA Streptococcus mitis NCTC 12261

57.252

98.744

0.565
  htrA Streptococcus pneumoniae R6

57.252

98.744

0.565
  htrA Streptococcus pneumoniae Rx1

57.252

98.744

0.565