Detailed information NTG0918816

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: VNN46_RS04845
• Genome accession: NZ_CP141719
• Coordinates: 979078..980013 (+)
• Length: 311 a.a.
• NCBI ID: WP_003133316.1
• Uniprot ID: A0A1I4GTA7
• Organism: Lactococcus garvieae strain CAHFS22LA20.5H7
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 974078..985013

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN46_RS04815 (VNN46_04815)	-	974509..974955 (+)	447	WP_003133306.1	DNA starvation/stationary phase protection protein	-
VNN46_RS04820 (VNN46_04820)	-	974995..975375 (-)	381	WP_003133308.1	rhodanese-like domain-containing protein	-
VNN46_RS04825 (VNN46_04825)	-	975395..976360 (-)	966	WP_338962997.1	ROK family glucokinase	-
VNN46_RS04830 (VNN46_04830)	-	976353..976565 (-)	213	WP_003133311.1	YqgQ family protein	-
VNN46_RS04835 (VNN46_04835)	typA	976886..978727 (+)	1842	WP_003133313.1	translational GTPase TypA	-
VNN46_RS04840 (VNN46_04840)	-	978802..979032 (+)	231	WP_003133314.1	DUF3165 family protein	-
VNN46_RS04845 (VNN46_04845)	comYH	979078..980013 (+)	936	WP_003133316.1	class I SAM-dependent methyltransferase	Machinery gene
VNN46_RS04850 (VNN46_04850)	-	980098..981291 (+)	1194	WP_042218440.1	acetate kinase	-
VNN46_RS04855 (VNN46_04855)	-	981411..982604 (+)	1194	WP_003133320.1	acetate kinase	-
VNN46_RS04860 (VNN46_04860)	pyrH	982695..983411 (+)	717	WP_003133322.1	UMP kinase	-
VNN46_RS04865 (VNN46_04865)	frr	983441..983998 (+)	558	WP_003133324.1	ribosome recycling factor	-
VNN46_RS04870 (VNN46_04870)	-	984106..984966 (+)	861	WP_003133325.1	S1 RNA-binding domain-containing protein	-

Sequence

Protein

• Length: 311 a.a.
• Molecular weight: 35124.17 Da
• Isoelectric Point: 4.6693

>NTDB_id=918816 VNN46_RS04845 WP_003133316.1 979078..980013(+) (comYH) [Lactococcus garvieae strain CAHFS22LA20.5H7]
MDIEKIEKAFGLVLENIMAIQAELLTDFYDAFVEQNAAYLGALEFASLTKENNDKVRSMNLTKSEWQKLFQFVLLQGSRV
APMQANHNLTPDSIGFIFNFIIEELHKERKIRVLEFGSGTGNLAETLLVHMQKEVDYVGFEVDDLLLDLSASMSEVMGTE
ASFLQIDAVKPQPLESVDVVMSDLPVGYYPDDDTARHFQVHDKSEHTYVHHLMIEQSFKYLKESGFALFLAPDNLLTSAQ
SEFLKAWIKEHAHVAAVITLPSSLFKGAGKSIYLLSKNQTNTPTFVYPLADLADRSILQEFMSEFVKNVKI

Nucleotide

• Length: 936 bp

>NTDB_id=918816 VNN46_RS04845 WP_003133316.1 979078..980013(+) (comYH) [Lactococcus garvieae strain CAHFS22LA20.5H7]
ATGGATATAGAGAAAATCGAAAAAGCCTTTGGATTGGTTCTTGAAAATATTATGGCAATTCAAGCGGAGCTCTTGACGGA
TTTTTATGATGCTTTTGTGGAACAAAATGCAGCTTACTTAGGCGCTTTAGAGTTTGCATCTCTGACGAAGGAAAATAATG
ATAAGGTTCGTTCAATGAACCTCACGAAAAGTGAGTGGCAAAAGCTGTTTCAGTTTGTCTTGCTTCAAGGGTCACGTGTC
GCACCAATGCAAGCAAATCATAATTTAACACCAGATTCTATTGGGTTTATCTTTAATTTCATCATTGAAGAGTTGCACAA
AGAAAGAAAGATTCGTGTACTAGAATTTGGCTCAGGAACAGGGAATTTAGCGGAAACGCTCTTGGTTCATATGCAAAAAG
AAGTAGACTATGTTGGTTTTGAAGTAGATGACCTCTTGTTGGATTTGTCCGCTTCAATGTCAGAAGTCATGGGAACAGAA
GCAAGTTTTCTCCAAATTGACGCCGTGAAACCACAGCCCTTGGAGTCTGTAGATGTTGTGATGAGTGATCTCCCGGTTGG
TTACTATCCAGACGATGACACTGCTCGCCATTTTCAAGTGCATGACAAATCAGAACATACCTATGTGCACCACTTAATGA
TTGAGCAATCCTTTAAGTATCTGAAGGAGAGTGGTTTTGCGCTCTTCTTAGCTCCAGATAATCTTTTGACAAGTGCACAG
TCAGAATTTTTGAAGGCTTGGATTAAAGAACATGCACATGTTGCTGCAGTCATTACATTGCCTTCATCACTCTTTAAAGG
TGCAGGAAAATCGATTTATTTATTAAGTAAAAACCAAACAAATACACCAACTTTTGTTTACCCCTTGGCTGATTTAGCAG
ACCGTTCTATTTTGCAAGAATTTATGTCTGAGTTTGTGAAAAATGTCAAGATTTGA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (132-286)

3D structure

• AlphaFold DB: A0A1I4GTA7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	49.677	99.678	0.495
comYH	Streptococcus mutans UA159	49.355	99.678	0.492