Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AABK14_RS12765 Genome accession   NZ_AP027886
Coordinates   2597845..2598477 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2018-05-5CC     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2592845..2603477
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABK14_RS12740 (VEE47_24530) yheS 2593014..2594927 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  AABK14_RS12745 (VEE47_24540) yheT 2594927..2595949 (+) 1023 WP_000057379.1 hydrolase -
  AABK14_RS12750 (VEE47_24550) yheU 2595943..2596161 (+) 219 WP_000907085.1 YheU family protein -
  AABK14_RS12755 (VEE47_24560) prkB 2596215..2597084 (+) 870 WP_001274680.1 phosphoribulokinase -
  AABK14_RS12760 (VEE47_24570) yhfA 2597139..2597543 (-) 405 WP_001148910.1 OsmC family protein -
  AABK14_RS12765 (VEE47_24580) crp 2597845..2598477 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AABK14_RS12770 (VEE47_24590) yhfK 2598528..2600618 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AABK14_RS12775 (VEE47_24600) argD 2600685..2601905 (-) 1221 WP_000963768.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AABK14_RS12780 (VEE47_24610) pabA 2601991..2602554 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  AABK14_RS12785 (VEE47_24620) fic 2602586..2603188 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AABK14_RS12790 (VEE47_24630) yhfG 2603178..2603345 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=91439 AABK14_RS12765 WP_000242755.1 2597845..2598477(+) (crp) [Escherichia coli strain 2018-05-5CC]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=91439 AABK14_RS12765 WP_000242755.1 2597845..2598477(+) (crp) [Escherichia coli strain 2018-05-5CC]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment