Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   U0N78_RS00375 Genome accession   NZ_CP140109
Coordinates   65875..66777 (+) Length   300 a.a.
NCBI ID   WP_043025662.1    Uniprot ID   A0A0Z8FP58
Organism   Streptococcus suis strain 2022WUSS148     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 60875..71777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS00355 (U0N78_00355) - 62452..63720 (+) 1269 WP_197315070.1 MerR family transcriptional regulator -
  U0N78_RS00360 (U0N78_00360) ruvB 63914..64915 (+) 1002 WP_043025656.1 Holliday junction branch migration DNA helicase RuvB -
  U0N78_RS00365 (U0N78_00365) - 64915..65124 (+) 210 WP_043025657.1 GNAT family N-acetyltransferase -
  U0N78_RS00370 (U0N78_00370) - 65181..65804 (+) 624 WP_043025659.1 HAD-IA family hydrolase -
  U0N78_RS00375 (U0N78_00375) comR 65875..66777 (+) 903 WP_043025662.1 helix-turn-helix domain-containing protein Regulator
  U0N78_RS00380 (U0N78_00380) - 66986..68206 (+) 1221 WP_043025663.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  U0N78_RS00385 (U0N78_00385) - 68397..69920 (+) 1524 WP_043025665.1 quinol oxidase -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35420.52 Da        Isoelectric Point: 4.3999

>NTDB_id=912553 U0N78_RS00375 WP_043025662.1 65875..66777(+) (comR) [Streptococcus suis strain 2022WUSS148]
MNDKEFGQRVRQLRETANLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIHRKKQFSVND
LLIIQLYLINLRMEVKQSSDFQYFLELVEKFPSQVELVESGDLFILRDVMITSVGLLGQKEEFSYIPTLFEALDKIMQKT
QDFQKKPILNLLKWKYELLINKDKDAATALYEEALLFARIIGNAHLTAKLEEEWRKDSQL

Nucleotide


Download         Length: 903 bp        

>NTDB_id=912553 U0N78_RS00375 WP_043025662.1 65875..66777(+) (comR) [Streptococcus suis strain 2022WUSS148]
ATGAACGATAAGGAATTTGGGCAGCGTGTGCGTCAACTGCGAGAAACTGCTAATCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAACTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTACGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTACTTCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGGGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCCGAGGAGGAGAAAATAGCAATCGATGCTATTCAATCTATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAGATACATAGAAAAAAACAATTTTCAGTCAATGAT
TTGTTGATAATCCAGCTCTATTTAATCAATTTGAGAATGGAAGTTAAACAGAGTAGTGATTTCCAGTATTTTTTAGAGTT
GGTTGAAAAGTTTCCGAGCCAAGTAGAATTAGTTGAATCTGGGGATTTGTTTATTTTAAGGGATGTGATGATAACTTCTG
TTGGACTTTTGGGACAAAAGGAAGAATTTAGCTATATTCCTACACTCTTTGAAGCACTTGATAAGATAATGCAGAAGACC
CAAGATTTTCAAAAGAAACCTATTCTTAATCTGCTTAAGTGGAAATATGAGTTGTTAATAAATAAAGATAAAGATGCAGC
AACTGCCTTATATGAAGAAGCACTTCTTTTTGCAAGAATAATTGGTAATGCACACCTAACGGCTAAATTAGAAGAAGAGT
GGAGAAAAGATAGTCAATTATAG

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8FP58

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

66.89

99.667

0.667
  comR Streptococcus suis 05ZYH33

66.89

99.667

0.667
  comR Streptococcus suis D9

60.465

100

0.607
  comR Streptococcus mutans UA159

43.478

99.667

0.433
  comR Streptococcus pyogenes MGAS8232

39.865

98.667

0.393
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

40.345

96.667

0.39
  comR Streptococcus pyogenes MGAS315

36.242

99.333

0.36