Detailed information NTG0911368

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: U0448_RS08660
• Genome accession: NZ_CP139860
• Coordinates: 1698917..1699507 (+)
• Length: 196 a.a.
• NCBI ID: WP_000613477.1
• Uniprot ID: A0A064BX72
• Organism: Streptococcus pneumoniae strain 21011
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1693917..1704507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0448_RS08630	-	1694303..1694758 (-)	456	WP_001861299.1	8-oxo-dGTP diphosphatase	-
U0448_RS08635	-	1694778..1695953 (-)	1176	WP_000680053.1	NAD(P)/FAD-dependent oxidoreductase	-
U0448_RS08640	-	1696012..1696857 (-)	846	WP_000219939.1	DegV family protein	-
U0448_RS08645	-	1696982..1697539 (+)	558	WP_000004139.1	TetR/AcrR family transcriptional regulator	-
U0448_RS08650	-	1697558..1698025 (+)	468	WP_000136976.1	cytidine/deoxycytidylate deaminase family protein	-
U0448_RS08655	upp	1698114..1698743 (+)	630	WP_050266021.1	uracil phosphoribosyltransferase	-
U0448_RS08660	clpP	1698917..1699507 (+)	591	WP_000613477.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
U0448_RS08665	-	1699586..1699834 (+)	249	WP_000462126.1	YlbG family protein	-
U0448_RS08670	-	1699936..1701096 (+)	1161	WP_000726146.1	ABC transporter substrate-binding protein	-
U0448_RS08675	-	1701364..1702233 (+)	870	WP_000941421.1	branched-chain amino acid ABC transporter permease	-
U0448_RS08680	-	1702237..1703193 (+)	957	WP_000662293.1	branched-chain amino acid ABC transporter permease	-
U0448_RS08685	-	1703193..1703957 (+)	765	WP_001186003.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21358.36 Da
• Isoelectric Point: 4.4910

>NTDB_id=911368 U0448_RS08660 WP_000613477.1 1698917..1699507(+) (clpP) [Streptococcus pneumoniae strain 21011]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=911368 U0448_RS08660 WP_000613477.1 1698917..1699507(+) (clpP) [Streptococcus pneumoniae strain 21011]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAACTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A064BX72

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	100	100	1
clpP	Streptococcus pneumoniae D39	100	100	1
clpP	Streptococcus pneumoniae R6	100	100	1
clpP	Streptococcus pneumoniae TIGR4	100	100	1
clpP	Streptococcus thermophilus LMG 18311	92.821	99.49	0.923
clpP	Streptococcus thermophilus LMD-9	92.821	99.49	0.923
clpP	Streptococcus pyogenes JRS4	90.769	99.49	0.903
clpP	Streptococcus pyogenes MGAS315	90.769	99.49	0.903
clpP	Streptococcus mutans UA159	85.714	100	0.857
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Bacillus subtilis subsp. subtilis str. 168	58.854	97.959	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571