Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   SID94_RS02165 Genome accession   NZ_CP139039
Coordinates   450181..451305 (+) Length   374 a.a.
NCBI ID   WP_000228517.1    Uniprot ID   E2QFE2
Organism   Escherichia coli MP1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 445181..456305
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SID94_RS02140 (SID94_02140) mscL 445304..445717 (-) 414 WP_000022445.1 large-conductance mechanosensitive channel protein MscL -
  SID94_RS02145 (SID94_02145) trkA 445847..447223 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  SID94_RS02150 (SID94_02150) rsmB 447245..448534 (-) 1290 WP_001765229.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SID94_RS02155 (SID94_02155) fmt 448580..449527 (-) 948 WP_001765230.1 methionyl-tRNA formyltransferase -
  SID94_RS02160 (SID94_02160) def 449542..450051 (-) 510 WP_000114984.1 peptide deformylase -
  SID94_RS02165 (SID94_02165) dprA 450181..451305 (+) 1125 WP_000228517.1 DNA-protecting protein DprA Machinery gene
  SID94_RS02170 (SID94_02170) smg 451277..451750 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  SID94_RS02175 (SID94_02175) yrdD 451779..452321 (+) 543 WP_001312137.1 type I DNA topoisomerase -
  SID94_RS02180 (SID94_02180) tsaC 452326..452898 (+) 573 WP_001765231.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  SID94_RS02185 (SID94_02185) aroE 452903..453721 (+) 819 WP_001765233.1 shikimate dehydrogenase -
  SID94_RS02190 (SID94_02190) yrdB 453718..453975 (+) 258 WP_001765234.1 DUF1488 domain-containing protein -
  SID94_RS02195 (SID94_02195) yrdA 453951..454505 (-) 555 WP_001525792.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40910.86 Da        Isoelectric Point: 6.0395

>NTDB_id=906905 SID94_RS02165 WP_000228517.1 450181..451305(+) (dprA) [Escherichia coli MP1]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=906905 SID94_RS02165 WP_000228517.1 450181..451305(+) (dprA) [Escherichia coli MP1]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGCCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39