Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   SJJ73_RS05095 Genome accession   NZ_CP138904
Coordinates   1097823..1099973 (+) Length   716 a.a.
NCBI ID   WP_172437030.1    Uniprot ID   -
Organism   Weissella cibaria strain BWL4     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1096753..1115408 1097823..1099973 within 0


Gene organization within MGE regions


Location: 1096753..1115408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SJJ73_RS05090 - 1096753..1096920 (+) 168 WP_172437029.1 hypothetical protein -
  SJJ73_RS05095 comA 1097823..1099973 (+) 2151 WP_172437030.1 peptide cleavage/export ABC transporter Regulator
  SJJ73_RS05100 - 1099983..1101353 (+) 1371 WP_386119920.1 bacteriocin secretion accessory protein -
  SJJ73_RS05105 - 1101356..1101634 (+) 279 WP_099087966.1 helix-turn-helix transcriptional regulator -
  SJJ73_RS05110 - 1101758..1101916 (+) 159 WP_172437031.1 hypothetical protein -
  SJJ73_RS05115 - 1101922..1102083 (+) 162 WP_143699568.1 lactococcin G-beta/enterocin 1071B family bacteriocin -
  SJJ73_RS05120 - 1102132..1102728 (+) 597 WP_099087967.1 CPBP family intramembrane glutamic endopeptidase -
  SJJ73_RS05125 - 1102785..1102916 (+) 132 WP_186433891.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SJJ73_RS05130 - 1103202..1103372 (+) 171 WP_099087968.1 bacteriocin -
  SJJ73_RS05135 - 1103397..1103558 (+) 162 WP_172437032.1 hypothetical protein -
  SJJ73_RS05140 - 1103620..1104306 (+) 687 WP_099087969.1 CPBP family intramembrane glutamic endopeptidase -
  SJJ73_RS05145 - 1105544..1106761 (+) 1218 WP_099087972.1 CCA tRNA nucleotidyltransferase -
  SJJ73_RS05150 - 1106765..1108654 (+) 1890 WP_145461201.1 ABC-F family ATP-binding cassette domain-containing protein -
  SJJ73_RS05155 - 1108661..1109158 (+) 498 WP_085638433.1 dihydrofolate reductase -
  SJJ73_RS05160 - 1109263..1109463 (+) 201 WP_010371776.1 YjzD family protein -
  SJJ73_RS05165 - 1109586..1112969 (+) 3384 WP_099087974.1 DNA polymerase III subunit alpha -
  SJJ73_RS05170 - 1113174..1115408 (+) 2235 WP_145461202.1 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 79273.50 Da        Isoelectric Point: 6.6034

>NTDB_id=905789 SJJ73_RS05095 WP_172437030.1 1097823..1099973(+) (comA) [Weissella cibaria strain BWL4]
MSKVKLKRYVSQVDERDCGVAALSMITNQYGSSYSLARLREEAKTDLEGTTALGITQASENLGFDTRAIRADKTLFDISD
IPLPFIAHVIKADSFLHYYVVYGYDGKYIWLADPDRSVGKIKMSIERFEHEWSGVSIFIAPKPDYRPDKDDQSNFYSFLP
IILKQKGTITLVVLAALMVTVISISGSYYLQAIVDTYIPNGMKSTLGIMSLGLIVAYGVQQVLGFSRDYLLAVIGQRLAI
DVILSYIKHLFELPVSFYATRRTGEITSRFGDANSIIDAAASTILTLFLDVGTIIIVGSVLAIQDIQLFCITLGSLPMYI
FIVWLFKRPFEKMNNNTMQSNAMLNSSIIEDINGMETIKALTGEQESYQKIDREFVDYLDKSFIYQKTMAFQAAIKGGTK
LLVNVSVLWVGAQLVMNNTISLGQLVTYNALLGYFTDPLQSIIDLQTKLQSAAVANNRLNEVYLVTSEFGASSMKNKRIQ
NGDIKLNDVTYKYGFGRNALDHVSLDIKKGSKVALVGISGSGKSTLVKSIIQFLTPESGQIVIGGQDTARVDKTNLRRMI
TYVPQSPFIFTGSVRENLLLGSSPDVTNEDVITALKNAHIMSDIEQMPQGIETEISEDGGMSGGQKQRIAIARALLTRSP
ILILDESTSNLDVLTEKQVIDNLMKLDKTIIFVAHRLTIAERSEQVVVMSRGKVVESGTHDELMATGKFYAQLVNH

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=905789 SJJ73_RS05095 WP_172437030.1 1097823..1099973(+) (comA) [Weissella cibaria strain BWL4]
TTGTCAAAGGTTAAATTGAAAAGATATGTATCACAAGTTGATGAGCGAGATTGTGGAGTTGCGGCGTTGTCCATGATAAC
GAATCAGTATGGATCAAGTTATTCTCTTGCCAGGTTACGCGAGGAAGCAAAAACTGATTTAGAAGGTACAACGGCATTAG
GAATTACGCAAGCATCTGAAAATTTAGGATTTGATACGCGAGCAATTCGAGCAGATAAGACGTTGTTTGATATATCTGAT
ATTCCATTACCTTTTATAGCACACGTGATTAAAGCAGATAGTTTCCTGCATTATTATGTCGTATATGGGTATGATGGAAA
ATATATTTGGTTGGCTGATCCTGATCGTTCGGTAGGGAAAATAAAAATGTCAATAGAACGGTTTGAGCATGAATGGTCTG
GAGTTTCAATATTTATTGCTCCTAAACCAGATTACAGACCTGATAAGGACGATCAAAGTAACTTTTATTCTTTTTTACCT
ATTATTCTTAAGCAAAAAGGAACAATCACGTTGGTAGTACTTGCAGCGCTGATGGTAACCGTTATTAGTATTTCTGGATC
GTACTATTTACAAGCAATTGTTGATACATATATTCCCAATGGTATGAAAAGCACTTTAGGAATAATGTCATTAGGTTTGA
TTGTGGCATACGGTGTTCAGCAAGTACTTGGCTTTAGTCGGGATTATTTGCTAGCTGTTATTGGACAACGGTTAGCCATA
GATGTCATATTGTCGTACATTAAGCATTTGTTTGAATTACCGGTTTCTTTTTACGCGACGCGACGCACTGGAGAAATTAC
ATCACGGTTTGGCGATGCCAATTCAATTATTGATGCAGCAGCCAGTACGATACTGACACTGTTTTTAGATGTTGGAACAA
TTATTATTGTTGGCAGCGTACTTGCTATTCAAGATATCCAACTTTTCTGCATTACGCTAGGTTCATTACCGATGTACATA
TTCATTGTTTGGTTATTTAAAAGGCCTTTTGAGAAAATGAATAACAACACCATGCAGAGTAATGCGATGCTTAATTCATC
AATCATTGAAGATATTAATGGCATGGAGACGATTAAAGCTCTTACGGGAGAACAAGAAAGTTATCAGAAAATCGATCGTG
AATTTGTTGATTATTTGGATAAGTCATTTATTTATCAAAAAACAATGGCCTTTCAGGCTGCAATAAAAGGCGGAACAAAA
TTATTAGTAAATGTGTCTGTTTTGTGGGTTGGTGCGCAACTTGTAATGAATAATACGATTAGTTTGGGCCAGTTGGTAAC
GTATAATGCGCTCTTGGGGTATTTCACAGATCCATTGCAAAGCATTATCGATTTGCAGACGAAGTTGCAGTCTGCAGCCG
TTGCAAATAATCGATTGAATGAGGTGTATTTAGTGACGTCTGAATTCGGTGCTAGTTCAATGAAGAATAAGCGAATTCAA
AATGGTGATATTAAGTTAAATGACGTTACTTATAAGTACGGATTTGGACGTAATGCCCTTGATCATGTGTCATTAGATAT
AAAAAAAGGGTCTAAGGTTGCTTTGGTTGGGATAAGTGGATCCGGCAAATCTACTCTAGTTAAGAGCATCATTCAATTTC
TAACTCCAGAATCTGGTCAAATAGTCATAGGTGGTCAAGATACGGCTCGTGTTGATAAAACAAATTTACGACGGATGATT
ACATATGTTCCTCAGTCACCATTCATATTTACGGGTAGCGTAAGAGAAAATTTGCTATTAGGTTCGTCACCTGATGTAAC
GAATGAGGATGTGATTACTGCTCTTAAAAATGCACATATTATGTCGGACATTGAACAGATGCCTCAAGGAATTGAAACTG
AAATTTCAGAAGATGGGGGAATGTCTGGGGGACAAAAGCAGCGTATCGCGATTGCGCGTGCCTTACTAACTAGATCACCA
ATTTTGATTTTAGATGAATCAACCAGTAATTTGGATGTTTTGACGGAAAAGCAAGTGATTGATAATCTGATGAAACTTGA
TAAGACGATTATTTTTGTTGCTCATCGTTTGACTATTGCAGAACGTTCAGAGCAGGTAGTTGTGATGAGCAGAGGGAAGG
TGGTTGAGTCAGGAACACATGATGAATTGATGGCAACTGGTAAATTCTACGCGCAGTTGGTTAATCACTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(8-143)

ABC transporter transmembrane region (ABC_membrane)

(170-439)

ABC transporter (ABC_tran)

(500-649)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

58.509

99.302

0.581
  comA Streptococcus mitis NCTC 12261

58.228

99.302

0.578
  comA Streptococcus pneumoniae D39

57.947

99.302

0.575
  comA Streptococcus pneumoniae R6

57.947

99.302

0.575
  comA Streptococcus pneumoniae Rx1

57.947

99.302

0.575
  comA Streptococcus gordonii str. Challis substr. CH1

57.343

99.86

0.573
  comA Streptococcus pneumoniae TIGR4

57.665

99.302

0.573
  comA/nlmT Streptococcus mutans UA159

56.189

100

0.564