Detailed information NTG0905321

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGQ70_RS09660
• Genome accession: NZ_CP138864
• Coordinates: 1972457..1973500 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 136
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1967457..1978500

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ70_RS09630 (SGQ70_09625)	-	1967878..1969134 (-)	1257	WP_075583716.1	aminopeptidase	-
SGQ70_RS09635 (SGQ70_09630)	-	1969137..1969337 (-)	201	WP_000180460.1	DUF1128 family protein	-
SGQ70_RS09640 (SGQ70_09635)	-	1969484..1969948 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SGQ70_RS09645 (SGQ70_09640)	-	1969955..1970230 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SGQ70_RS09650 (SGQ70_09645)	-	1970508..1971725 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SGQ70_RS09655 (SGQ70_09650)	vraR	1971838..1972467 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGQ70_RS09660 (SGQ70_09655)	vraS	1972457..1973500 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGQ70_RS09665 (SGQ70_09660)	liaF	1973497..1974198 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGQ70_RS09670 (SGQ70_09665)	-	1974213..1974599 (-)	387	WP_001110179.1	hypothetical protein	-
SGQ70_RS09675 (SGQ70_09670)	map	1974816..1975574 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SGQ70_RS09680 (SGQ70_09675)	-	1976103..1977089 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
SGQ70_RS09685 (SGQ70_09680)	-	1977520..1977933 (-)	414	WP_001670387.1	hypothetical protein	-
SGQ70_RS09690 (SGQ70_09685)	-	1977962..1978072 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=905321 SGQ70_RS09660 WP_001017131.1 1972457..1973500(-) (vraS) [Staphylococcus aureus strain 136]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=905321 SGQ70_RS09660 WP_001017131.1 1972457..1973500(-) (vraS) [Staphylococcus aureus strain 136]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1