Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABC804_RS09020 Genome accession   NZ_CP155536
Coordinates   1714666..1715298 (-) Length   210 a.a.
NCBI ID   WP_000698438.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M264-3     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1709666..1720298
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC804_RS08995 (ABC804_08990) tig 1710698..1711981 (-) 1284 WP_000116468.1 trigger factor -
  ABC804_RS09000 (ABC804_08995) - 1712142..1712480 (-) 339 WP_001812733.1 tyrosine-type recombinase/integrase -
  ABC804_RS09005 (ABC804_09000) cbpG 1712836..1713426 (-) 591 Protein_1728 choline-binding protein CbpG -
  ABC804_RS09010 (ABC804_09005) - 1713507..1713746 (-) 240 WP_000754501.1 hypothetical protein -
  ABC804_RS09015 (ABC804_09010) - 1713896..1714665 (-) 770 Protein_1730 DNA alkylation repair protein -
  ABC804_RS09020 (ABC804_09020) vraR 1714666..1715298 (-) 633 WP_000698438.1 response regulator transcription factor Regulator
  ABC804_RS09025 (ABC804_09025) - 1715312..1716307 (-) 996 WP_000743662.1 sensor histidine kinase -
  ABC804_RS09030 (ABC804_09030) liaF 1716304..1717002 (-) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  ABC804_RS09035 (ABC804_09035) fni 1717080..1718090 (-) 1011 WP_000210616.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ABC804_RS09040 (ABC804_09040) - 1718074..1719081 (-) 1008 WP_000562427.1 phosphomevalonate kinase -
  ABC804_RS09045 (ABC804_09045) mvaD 1719068..1720021 (-) 954 WP_000373456.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23583.06 Da        Isoelectric Point: 4.5791

>NTDB_id=897225 ABC804_RS09020 WP_000698438.1 1714666..1715298(-) (vraR) [Streptococcus pneumoniae strain M264-3]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQATVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=897225 ABC804_RS09020 WP_000698438.1 1714666..1715298(-) (vraR) [Streptococcus pneumoniae strain M264-3]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGACTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41