Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABC811_RS08310 Genome accession   NZ_CP155535
Coordinates   1611777..1612409 (-) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain PJ755/1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1606777..1617409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC811_RS08280 (ABC811_08280) tig 1607812..1609095 (-) 1284 WP_000116462.1 trigger factor -
  ABC811_RS08285 (ABC811_08285) - 1609289..1609594 (-) 306 WP_001821501.1 tyrosine-type recombinase/integrase -
  ABC811_RS08290 (ABC811_08290) cbpG 1609950..1610540 (-) 591 Protein_1641 choline-binding protein CbpG -
  ABC811_RS08295 (ABC811_08295) - 1610621..1610860 (-) 240 WP_000754502.1 hypothetical protein -
  ABC811_RS08300 (ABC811_08300) - 1611010..1611552 (-) 543 Protein_1643 DNA alkylation repair protein -
  ABC811_RS08305 (ABC811_08305) - 1611534..1611776 (-) 243 WP_001854757.1 DNA alkylation repair protein -
  ABC811_RS08310 (ABC811_08310) vraR 1611777..1612409 (-) 633 WP_000698434.1 response regulator transcription factor Regulator
  ABC811_RS08315 (ABC811_08315) - 1612423..1613418 (-) 996 WP_000743686.1 sensor histidine kinase -
  ABC811_RS08320 (ABC811_08320) liaF 1613415..1614113 (-) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  ABC811_RS08325 (ABC811_08325) fni 1614191..1615201 (-) 1011 WP_000210618.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ABC811_RS08330 (ABC811_08330) - 1615185..1616192 (-) 1008 WP_000562440.1 phosphomevalonate kinase -
  ABC811_RS08335 (ABC811_08335) mvaD 1616179..1617132 (-) 954 WP_000373452.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=897065 ABC811_RS08310 WP_000698434.1 1611777..1612409(-) (vraR) [Streptococcus pneumoniae strain PJ755/1]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=897065 ABC811_RS08310 WP_000698434.1 1611777..1612409(-) (vraR) [Streptococcus pneumoniae strain PJ755/1]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41