Detailed information NTG0895330

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R4713_RS04055
• Genome accession: NZ_CP137103
• Coordinates: 768243..769280 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 21334
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 763243..774280

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4713_RS04030	-	763982..765313 (-)	1332	WP_000390039.1	hemolysin family protein	-
R4713_RS04035	endA	765604..766428 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
R4713_RS04040	-	766467..766655 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
R4713_RS04045	murA	766648..767931 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R4713_RS04050	-	767955..768185 (-)	231	WP_000615437.1	DUF1146 family protein	-
R4713_RS04055	sepM	768243..769280 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
R4713_RS04060	coaD	769264..769752 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
R4713_RS04065	rsmD	769742..770281 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R4713_RS04070	asnA	770346..771338 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
R4713_RS04075	-	771450..772133 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
R4713_RS04080	-	772189..772929 (-)	741	WP_000152701.1	RNA methyltransferase	-
R4713_RS04085	-	772963..773241 (+)	279	WP_001174613.1	acylphosphatase	-
R4713_RS04090	yidC	773319..774245 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=895330 R4713_RS04055 WP_000727280.1 768243..769280(-) (sepM) [Streptococcus pneumoniae strain 21334]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=895330 R4713_RS04055 WP_000727280.1 768243..769280(-) (sepM) [Streptococcus pneumoniae strain 21334]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591