Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   R1T10_RS02185 Genome accession   NZ_CP136807
Coordinates   400578..401042 (+) Length   154 a.a.
NCBI ID   WP_194732767.1    Uniprot ID   -
Organism   Neisseria meningitidis NMB     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 401130..414599 400578..401042 flank 88


Gene organization within MGE regions


Location: 400578..414599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1T10_RS02185 comE 400578..401042 (+) 465 WP_194732767.1 ComEA family DNA-binding protein Machinery gene
  R1T10_RS02190 comP 401130..401579 (+) 450 WP_002221685.1 type IV pilin protein Machinery gene
  R1T10_RS02195 - 401740..402063 (-) 324 WP_202052896.1 5'-nucleotidase -
  R1T10_RS02200 - 402276..402626 (+) 351 Protein_413 IS5/IS1182 family transposase -
  R1T10_RS02205 - 402652..403617 (-) 966 WP_002223479.1 IS30-like element IS1655 family transposase -
  R1T10_RS02210 - 403707..403832 (+) 126 Protein_415 IS5/IS1182 family transposase -
  R1T10_RS02215 - 404238..405293 (+) 1056 WP_002221681.1 DNA cytosine methyltransferase -
  R1T10_RS02220 - 405307..406953 (+) 1647 WP_002214929.1 TIGR02391 family protein -
  R1T10_RS02225 - 406957..407379 (+) 423 WP_002214928.1 very short patch repair endonuclease -
  R1T10_RS02230 - 407402..409264 (-) 1863 Protein_419 DUF3418 domain-containing protein -
  R1T10_RS02235 - 409661..410839 (-) 1179 Protein_420 DUF3418 domain-containing protein -
  R1T10_RS02240 lpt3 410941..412518 (-) 1578 WP_002226775.1 lipooligosaccharide phosphoethanolamine transferase -
  R1T10_RS02245 - 412730..412912 (-) 183 WP_002223144.1 hypothetical protein -
  R1T10_RS02250 - 412956..414599 (-) 1644 WP_002223143.1 AAA family ATPase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16533.78 Da        Isoelectric Point: 10.9695

>NTDB_id=892833 R1T10_RS02185 WP_194732767.1 400578..401042(+) (comE) [Neisseria meningitidis NMB]
MLYPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPAIPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=892833 R1T10_RS02185 WP_194732767.1 400578..401042(+) (comE) [Neisseria meningitidis NMB]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGCTATACCGGCCGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

91.803

79.221

0.727
  comE Neisseria gonorrhoeae MS11

91.803

79.221

0.727
  comE Neisseria gonorrhoeae MS11

91.803

79.221

0.727
  comE Neisseria gonorrhoeae MS11

91.803

79.221

0.727