Detailed information NTG0887897

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RS960_RS09370
• Genome accession: NZ_CP135966
• Coordinates: 1901708..1902751 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ST5477
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1896708..1907751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RS960_RS09340 (RS960_09340)	-	1897126..1898382 (-)	1257	WP_001793428.1	aminopeptidase	-
RS960_RS09345 (RS960_09345)	-	1898385..1898585 (-)	201	WP_000180462.1	DUF1128 family protein	-
RS960_RS09350 (RS960_09350)	-	1898732..1899196 (+)	465	WP_317528642.1	low molecular weight protein-tyrosine-phosphatase	-
RS960_RS09355 (RS960_09355)	-	1899203..1899478 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RS960_RS09360 (RS960_09360)	-	1899756..1900973 (+)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
RS960_RS09365 (RS960_09365)	vraR	1901089..1901718 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
RS960_RS09370 (RS960_09370)	vraS	1901708..1902751 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RS960_RS09375 (RS960_09375)	liaF	1902748..1903449 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
RS960_RS09380 (RS960_09380)	-	1903464..1903850 (-)	387	WP_001110179.1	hypothetical protein	-
RS960_RS09385 (RS960_09385)	map	1904067..1904825 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RS960_RS09390 (RS960_09390)	-	1905354..1906340 (+)	987	WP_000999713.1	FUSC family protein	-
RS960_RS09395 (RS960_09395)	-	1906714..1907127 (-)	414	WP_262538798.1	hypothetical protein	-
RS960_RS09400 (RS960_09400)	-	1907156..1907268 (-)	113	Protein_1814	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=887897 RS960_RS09370 WP_001017131.1 1901708..1902751(-) (vraS) [Staphylococcus aureus strain ST5477]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=887897 RS960_RS09370 WP_001017131.1 1901708..1902751(-) (vraS) [Staphylococcus aureus strain ST5477]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCTCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1