Detailed information NTG0880329

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: RJW53_RS07770
• Genome accession: NZ_CP134488
• Coordinates: 1521621..1522970 (-)
• Length: 449 a.a.
• NCBI ID: WP_074392660.1
• Uniprot ID: -
• Organism: Streptococcus suis strain NLS50
• Function: repress competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1523888..1525609	1521621..1522970	flank	918

Gene organization within MGE regions

Location: 1521621..1525609

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RJW53_RS07770 (RJW53_07770)	micB	1521621..1522970 (-)	1350	WP_074392660.1	cell wall metabolism sensor histidine kinase VicK	Regulator
RJW53_RS07775 (RJW53_07775)	micA	1522963..1523667 (-)	705	WP_002935840.1	response regulator YycF	Regulator
RJW53_RS07780 (RJW53_07780)	-	1523888..1525609 (+)	1722	WP_074389404.1	IS1634 family transposase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51065.11 Da
• Isoelectric Point: 4.4860

>NTDB_id=880329 RJW53_RS07770 WP_074392660.1 1521621..1522970(-) (micB) [Streptococcus suis strain NLS50]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGYGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide

• Length: 1350 bp

>NTDB_id=880329 RJW53_RS07770 WP_074392660.1 1521621..1522970(-) (micB) [Streptococcus suis strain NLS50]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTTGTCGTCTTGCATGATATGACCGAGCAAGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTAT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTCAAGGTATCCTTGGATGAGACCAACCGCATGATGCGGATGATTACAGATCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTTATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• PAS fold (PAS) (96-199)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	70.183	97.105	0.682
vicK	Streptococcus mutans UA159	70.72	89.755	0.635