Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   OCX48_RS02630 Genome accession   NZ_AP024736
Coordinates   560421..560990 (+) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain 59709     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 555421..565990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCX48_RS02605 cysE 556634..557281 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  OCX48_RS02610 cysS 557265..558665 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  OCX48_RS02615 - 558658..559062 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  OCX48_RS02620 rlmB 559070..559816 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  OCX48_RS02625 - 559816..560340 (+) 525 WP_000664738.1 NYN domain-containing protein -
  OCX48_RS02630 sigH 560421..560990 (+) 570 WP_000872877.1 sigma-70 family RNA polymerase sigma factor Regulator
  OCX48_RS02635 rpmG 561105..561248 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  OCX48_RS02640 secE 561304..561486 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  OCX48_RS02645 nusG 561499..562047 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  OCX48_RS02650 rplK 562228..562650 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  OCX48_RS02655 rplA 562858..563550 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  OCX48_RS02660 rplJ 563823..564323 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  OCX48_RS02665 rplL 564366..564734 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  OCX48_RS02670 - 564909..565517 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=87978 OCX48_RS02630 WP_000872877.1 560421..560990(+) (sigH) [Staphylococcus aureus strain 59709]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=87978 OCX48_RS02630 WP_000872877.1 560421..560990(+) (sigH) [Staphylococcus aureus strain 59709]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment