Detailed information NTG0874524

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: RDV54_RS08370
• Genome accession: NZ_CP133471
• Coordinates: 1748233..1749243 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090627.1
• Uniprot ID: I0SX71
• Organism: Streptococcus mitis strain LMG 14557
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1743233..1754243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV54_RS08345 (RDV54_08345)	folP	1743829..1744803 (+)	975	WP_000240964.1	dihydropteroate synthase	-
RDV54_RS08350 (RDV54_08350)	-	1744805..1746127 (+)	1323	WP_000658435.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
RDV54_RS08355 (RDV54_08355)	folE	1746108..1746662 (+)	555	WP_000380931.1	GTP cyclohydrolase I FolE	-
RDV54_RS08360 (RDV54_08360)	folK	1746705..1747517 (+)	813	WP_000372493.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
RDV54_RS08365 (RDV54_08365)	-	1747678..1747995 (-)	318	WP_000886035.1	DUF960 domain-containing protein	-
RDV54_RS08370 (RDV54_08370)	ccpA	1748233..1749243 (+)	1011	WP_001090627.1	catabolite control protein A	Regulator
RDV54_RS08375 (RDV54_08375)	-	1749297..1750259 (-)	963	WP_001124765.1	asparaginase	-
RDV54_RS08380 (RDV54_08380)	-	1750325..1751716 (+)	1392	WP_078228369.1	Cof-type HAD-IIB family hydrolase	-
RDV54_RS08385 (RDV54_08385)	-	1751932..1752384 (-)	453	WP_000079148.1	universal stress protein	-
RDV54_RS08390 (RDV54_08390)	-	1752546..1752848 (+)	303	WP_000977176.1	hypothetical protein	-
RDV54_RS08395 (RDV54_08395)	-	1753005..1754219 (+)	1215	WP_000666474.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37169.19 Da
• Isoelectric Point: 5.3350

>NTDB_id=874524 RDV54_RS08370 WP_001090627.1 1748233..1749243(+) (ccpA) [Streptococcus mitis strain LMG 14557]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=874524 RDV54_RS08370 WP_001090627.1 1748233..1749243(+) (ccpA) [Streptococcus mitis strain LMG 14557]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACAGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAATACTCGTAAAAAAGTGCTTGAGGTGATTGACCGTTTGGATTACCGTCCAAATG
CAGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTGGTGATACCAAATATTACCAATGGTTATTTCTCA
ACGCTTGCCAAAGGGATTGATGATATTGCTGAAATGTACAAGTATAATATCGTTCTTGCTAATAGTGATGAGGATGATGA
TAAGGAAGTTTCAGTTGTCAATACCCTGTTTTCTAAGCAAGTGGATGGTATCATCTTTATGGGGTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGAACACCAGTTGTTCTTGCAGGAACTGTGGATGTAGAACACCAACTTCCAAGT
GTTAATATTGACTACAAACAAGCTACGATTGATGCAGTGACCTACCTTGCTAAAGAAAATGAGCGCATTGCTTTCGTAAG
CGGTCCACTAGTGGATGATATCAATGGTAAGGTTCGTTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGTATTTCTT
ATAGCGAAGGATTGGTATTTGAGTCTAAATACACTTATGAAGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCAAAC
GCAACTGCAGCAGTTGTAACAGGTGATGAGCTGGCAGCAGGTGTCTTGAACGGCCTTGCTGATAAGGGTGTATCAGTACC
AGAAGAATTTGAAATCATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACTATTGCCCAAC
CTCTTTATGACCTTGGGGCCATCAGTATGCGTATGTTGACCAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGCTCAACACGAAAACGGAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: I0SX71

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.536	100	0.955
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.521	99.405	0.89
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.006	98.512	0.571