Detailed information NTG0859680

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V74_RS09175
• Genome accession: NZ_CP130531
• Coordinates: 1898758..1899801 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA16-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1893758..1904801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V74_RS09145	-	1894179..1895435 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V74_RS09150	-	1895438..1895638 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V74_RS09155	-	1895785..1896249 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V74_RS09160	-	1896256..1896531 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V74_RS09165	-	1896809..1898026 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
Q3V74_RS09170	vraR	1898139..1898768 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V74_RS09175	vraS	1898758..1899801 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V74_RS09180	liaF	1899798..1900499 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V74_RS09185	-	1900514..1900900 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V74_RS09190	map	1901117..1901875 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V74_RS09195	-	1902404..1903390 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q3V74_RS09200	-	1903823..1904236 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V74_RS09205	-	1904265..1904375 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859680 Q3V74_RS09175 WP_001017131.1 1898758..1899801(-) (vraS) [Staphylococcus aureus strain SA16-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859680 Q3V74_RS09175 WP_001017131.1 1898758..1899801(-) (vraS) [Staphylococcus aureus strain SA16-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1