Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   V6U68_RS07120 Genome accession   NZ_CP145866
Coordinates   1569630..1571504 (-) Length   624 a.a.
NCBI ID   WP_410531519.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS9     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1564630..1576504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS07085 (V6U68_07065) rimM 1565011..1565529 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  V6U68_RS07100 (V6U68_07080) vraR 1566224..1566868 (-) 645 WP_002884791.1 response regulator transcription factor Regulator
  V6U68_RS07105 (V6U68_07085) - 1566858..1567868 (-) 1011 WP_201036009.1 sensor histidine kinase -
  V6U68_RS07110 (V6U68_07090) liaF 1567865..1568563 (-) 699 WP_073685667.1 cell wall-active antibiotics response protein LiaF -
  V6U68_RS07115 (V6U68_07095) - 1568726..1569484 (-) 759 WP_198463717.1 potassium channel family protein -
  V6U68_RS07120 (V6U68_07100) stkP/pknB 1569630..1571504 (-) 1875 WP_410531519.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V6U68_RS07125 (V6U68_07105) - 1571504..1572241 (-) 738 WP_037598574.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  V6U68_RS07130 (V6U68_07110) rsmB 1572284..1573606 (-) 1323 WP_347101515.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V6U68_RS07135 (V6U68_07115) fmt 1573596..1574531 (-) 936 WP_347101514.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 68006.86 Da        Isoelectric Point: 6.7045

>NTDB_id=853860 V6U68_RS07120 WP_410531519.1 1569630..1571504(-) (stkP/pknB) [Streptococcus salivarius strain KSS9]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSIAQTKIEGAGFKVGEVKEV
EDDSVDTGKVIKTDPIAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKNISSSSIEYHDYNTGAKLDKDKIPSSTEV
LYQDPQAGTSVDGTVILYVSVATVSSNLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=853860 V6U68_RS07120 WP_410531519.1 1569630..1571504(-) (stkP/pknB) [Streptococcus salivarius strain KSS9]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATTCTGGATAATGAAAAAGTGGCTATTAAGGTACTTCGTACCAATTACCAAACTGATCAGGTGG
CTGTGGCCCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAAATACATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTCCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACCAGTCTAACTCAAACGAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
TAAAGCGACTATCCAAAGTGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GCGATAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAACCACTACCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCTTTGGAAAATGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTACAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGTGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCGAAGGTTGATCCAGTTCCATCAGCAAGTCTTGAGAAAAAGGCGGTTGCTGCTGAACCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAAGAACTTCTTCTCAACCTTACTCAAGGT
TTTTCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTAGTCTTTACCAATCCTGATAATGTCCAAGTACCTA
ATGTGGTCGGTCAGGAGTTGTCCATAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTG
GAAGATGACTCTGTCGATACGGGTAAGGTCATCAAGACCGATCCTATAGCTGGAACCACACGAAAAGAAGGATCAAGCAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGTGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTAACGGTTTCAACAGCAGTTCAAACCTTGAATCGTAAGAATATCT
CAAGTAGTAGCATAGAGTACCACGACTATAATACTGGTGCTAAATTAGATAAGGATAAGATTCCTAGCAGTACGGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGTAAGTTCAAA
CCTTCAGTCTAGCTCAAGTAGTACGACACATTCGTCATCAACAAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAACTACAATAG

Domains

Predicted by InterProScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(511-580)

PASTA domain (PASTA)

(370-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.558

100

0.986
  pknB Streptococcus mutans UA159

66.974

86.859

0.582
  stkP Streptococcus pneumoniae TIGR4

52.265

91.987

0.481
  stkP Streptococcus pneumoniae D39

52.091

91.987

0.479
  stkP Streptococcus pneumoniae R6

52.091

91.987

0.479
  stkP Streptococcus pneumoniae Rx1

51.916

91.987

0.478