Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V6T01_RS07195 Genome accession   NZ_CP145856
Coordinates   1579262..1579906 (-) Length   214 a.a.
NCBI ID   WP_002891417.1    Uniprot ID   J7TMS3
Organism   Streptococcus salivarius strain KSS1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1574262..1584906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T01_RS07170 (V6T01_07145) - 1576338..1577336 (-) 999 WP_002891413.1 NAD(P)/FAD-dependent oxidoreductase -
  V6T01_RS07175 (V6T01_07150) trmD 1577338..1578057 (-) 720 WP_060972852.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  V6T01_RS07180 (V6T01_07155) rimM 1578047..1578565 (-) 519 WP_060972851.1 ribosome maturation factor RimM -
  V6T01_RS07195 (V6T01_07170) vraR 1579262..1579906 (-) 645 WP_002891417.1 response regulator transcription factor Regulator
  V6T01_RS07200 (V6T01_07175) - 1579896..1580906 (-) 1011 WP_002891418.1 sensor histidine kinase -
  V6T01_RS07205 (V6T01_07180) liaF 1580903..1581601 (-) 699 WP_195968864.1 cell wall-active antibiotics response protein LiaF -
  V6T01_RS07210 (V6T01_07185) - 1581764..1582522 (-) 759 WP_410541405.1 ion channel -
  V6T01_RS07215 (V6T01_07190) stkP/pknB 1582667..1584538 (-) 1872 WP_060972669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24007.33 Da        Isoelectric Point: 4.5814

>NTDB_id=852957 V6T01_RS07195 WP_002891417.1 1579262..1579906(-) (vraR) [Streptococcus salivarius strain KSS1]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEASNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=852957 V6T01_RS07195 WP_002891417.1 1579262..1579906(-) (vraR) [Streptococcus salivarius strain KSS1]
ATGTCGAATAAGATAAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGACTTAAGAGTTTCCTGAATCTCCA
AGGAGATGTCGAAGTGGTTGGAGAAGCGAGCAATGGCCGAGAAGGTGTTGACCTTGCCCTGGAACTTCGTCCAGATGTCG
TCGTAATGGACCTTGTCATGCCTGAATTAGATGGTGTTCAAGCGACTTTGGAATTGCTCAAAGAATGGCCAGAAGCCAAG
ATTTTGGTTTTGACTAGCTATTTAGACAATGAAAAAATTTATCCTGTCATTGAAGCTGGTGCTAAAGGCTATATGCTTAA
AACTAGTAGTGCGGCAGAGATTCTCAATAGTATCCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACTGAGGTGGACA
ATAAGATTAAATACCATGATAGCCATCCGGACCTACACGATGACTTGACGGCACGTGAACGTGATATCTTGGCCCTTTTG
GCTAAGGGTTATGACAATCAAACCATTGCTAATGAGCTATTTATTTCATTGAAAACCGTTAAAACTCACGTGTCTAATAT
CCTTGGAAAACTCAATGTTGATGACCGTACTCAGGCTGTGGTTTATGCCTTTAGACATCATTTGGTTTCGCAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TMS3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379