Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   QSU80_RS12050 Genome accession   NZ_CP128188
Coordinates   2468291..2470099 (-) Length   602 a.a.
NCBI ID   WP_002373090.1    Uniprot ID   A0A4Y3JL10
Organism   Enterococcus faecium strain A2     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2463291..2475099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QSU80_RS12025 - 2464339..2465238 (-) 900 WP_010732876.1 RluA family pseudouridine synthase -
  QSU80_RS12030 - 2465240..2466037 (-) 798 WP_002315658.1 NAD kinase -
  QSU80_RS12035 - 2466012..2466719 (-) 708 WP_002309982.1 GTP pyrophosphokinase family protein -
  QSU80_RS12040 - 2466850..2467425 (+) 576 WP_002373095.1 CYTH domain-containing protein -
  QSU80_RS12045 - 2467543..2468220 (+) 678 WP_002373092.1 ClpXP adapter SpxH family protein -
  QSU80_RS12050 pepF 2468291..2470099 (-) 1809 WP_002373090.1 oligoendopeptidase F Regulator
  QSU80_RS12055 - 2470279..2471277 (-) 999 WP_025478372.1 competence protein CoiA family protein -
  QSU80_RS12060 - 2471375..2472028 (-) 654 WP_002373086.1 adaptor protein MecA -
  QSU80_RS12065 spxA 2472359..2472757 (-) 399 WP_002296384.1 transcriptional regulator SpxA -
  QSU80_RS12070 - 2473522..2474229 (+) 708 WP_025478370.1 HAD family hydrolase -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69736.14 Da        Isoelectric Point: 4.7352

>NTDB_id=846607 QSU80_RS12050 WP_002373090.1 2468291..2470099(-) (pepF) [Enterococcus faecium strain A2]
MEVKQLPKREELPENLTWDLTKIFSSDQEFDKKYLELSEKLKKSEKYKGTLDQGASQFLDAIEFVLSVYRQTEIIYVYAH
LKNDQDTGNTEYQALYARASSLFSKVSEAVSWFEPEILQLSDERIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
LAGAGEIFEASSDTFAVLNNADLVFPTIEGENGEKVQLSHGVYGQLLESTDRSVREAAFKGLYSVYEQFRNTFASTLSTH
IKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVDVVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTY
EEAKEKALEALKPMGEEYMTIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHEMGHSVHSY
FTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHYLDGFKGTVFRQTQFAEFEHFMHTEDEKGVP
LTSEYLSDSYGKLNAKYYGPAVEEDPEIKFEWSRIPHFYYNYYVFQYSTGFSAASALAKRILSQEPDALENYLAYLKAGN
SDYPVEVMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=846607 QSU80_RS12050 WP_002373090.1 2468291..2470099(-) (pepF) [Enterococcus faecium strain A2]
ATGGAAGTAAAGCAGTTGCCAAAACGCGAAGAATTGCCTGAAAATTTAACTTGGGACTTGACCAAGATCTTTTCAAGCGA
CCAAGAATTTGATAAGAAATATCTAGAATTATCAGAAAAGTTAAAAAAATCTGAAAAATACAAAGGAACACTTGATCAAG
GCGCTTCTCAATTTCTTGATGCGATTGAATTTGTGTTGAGTGTTTATCGCCAAACTGAAATCATTTATGTCTATGCGCAC
CTTAAAAACGATCAAGATACTGGGAATACAGAATATCAAGCGCTTTATGCAAGAGCAAGTAGTTTGTTTTCAAAGGTTAG
TGAAGCTGTTTCCTGGTTTGAACCAGAAATATTGCAGTTATCAGATGAACGGATTTGGCAATATTTCAAAGAAGAACCGA
AGTTAGAAGTCTATCGTCACTATATCCAGCAAATAGTAGATAATCGTGCCCATGTTTTATCTGCCGAGCAGGAATCGCTT
CTTGCAGGAGCAGGTGAAATCTTTGAGGCTTCAAGTGATACATTTGCTGTTTTGAATAATGCAGATTTAGTTTTCCCAAC
GATCGAAGGAGAGAATGGTGAAAAAGTCCAATTATCTCATGGCGTGTACGGTCAGTTGCTAGAAAGCACGGATCGAAGTG
TTCGCGAAGCCGCATTTAAAGGGTTGTACAGTGTTTATGAACAATTTAGAAATACGTTTGCTTCTACTTTAAGTACGCAT
ATAAAAGGACATAATTTTAAAGCAAAAGTTCGTAATTACAGCTCTGCCAGAGAAGCATCTTTGAGCAATAATCATATTCC
TGAAAGTGTATACGACACTTTGGTAGATGTAGTAAACAAGCATTTGCCTTTGCTGCATCGATATATGGAATTACGGAAAC
GTTTATTAGAAGTGGAAAAACTGCACATGTACGATCTTTATACACCGGTCTTAGGAGAAGCTCCAATCACCTTTACGTAT
GAAGAAGCAAAAGAGAAAGCTTTGGAAGCACTGAAGCCAATGGGCGAAGAGTACATGACTATTGTAGAAAAAGCATTCTC
TGAACGTTGGATCGATGTTGTCGAAAATAAAGGAAAACGAAGTGGTGCCTATTCTTCGGGAAGCTATGACACAAATCCAT
ATATTTTATTGAATTGGCATGATACATTGGATCAGTTGTTTACGCTTGTCCACGAAATGGGACATAGTGTCCACAGTTAT
TTCACACGGTCGAACCAGCCTTATGTATACGGTGACTACTCCATCTTTTTAGCAGAAATTGCTTCGACAACGAACGAAAA
TATCCTAACAGAATATTTATTGGAAACAGAAAAAGACCCTCGCGTCCGAGCTTATGTGCTCAACCATTACTTGGATGGAT
TTAAAGGAACAGTTTTCCGCCAGACACAATTTGCTGAATTCGAGCACTTCATGCATACGGAAGATGAAAAAGGTGTGCCA
TTGACTAGTGAATATCTAAGTGATAGTTATGGTAAATTGAATGCAAAATATTATGGTCCGGCAGTCGAAGAAGATCCAGA
AATCAAATTTGAATGGTCACGGATCCCGCATTTTTACTATAATTACTATGTCTTCCAATACTCGACTGGTTTTTCTGCTG
CTTCAGCGTTGGCGAAAAGGATACTTAGTCAAGAACCAGATGCGCTAGAGAACTATTTGGCTTATCTAAAAGCTGGTAAC
AGTGATTATCCTGTTGAAGTGATGAAGAAAGCAGGAGTAGATATGACACAGGCTGCGTATATCGAAGATGCAATGTCGAT
GTTTGAACAACGACTAAATGAATTAGAAGAATTGATTGATCGTTTATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(116-185)

Peptidase family M3 (Peptidase_M3)

(206-586)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y3JL10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

55.818

98.505

0.55