Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   VKP39_RS08240 Genome accession   NZ_CP142353
Coordinates   1673238..1674005 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain D641     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1668238..1679005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP39_RS08225 (VKP39_08225) hexB 1668757..1670739 (-) 1983 WP_326623860.1 DNA mismatch repair endonuclease MutL Machinery gene
  VKP39_RS08230 (VKP39_08230) - 1670834..1671985 (-) 1152 WP_014635780.1 tyrosine-type recombinase/integrase -
  VKP39_RS08235 (VKP39_08235) - 1672234..1672377 (+) 144 WP_011185066.1 putative holin-like toxin -
  VKP39_RS08240 (VKP39_08240) irvR 1673238..1674005 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  VKP39_RS08245 (VKP39_08245) - 1674159..1674365 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  VKP39_RS08250 (VKP39_08250) - 1674399..1675166 (+) 768 WP_080277853.1 Bro-N domain-containing protein -
  VKP39_RS08255 (VKP39_08255) - 1675176..1675787 (+) 612 WP_326623861.1 Bro-N domain-containing protein -
  VKP39_RS08260 (VKP39_08260) - 1675807..1676214 (+) 408 WP_136262270.1 hypothetical protein -
  VKP39_RS08265 (VKP39_08265) - 1676227..1676844 (+) 618 WP_326623862.1 Rha family transcriptional regulator -
  VKP39_RS08270 (VKP39_08270) - 1677089..1677421 (+) 333 WP_326623863.1 hypothetical protein -
  VKP39_RS08275 (VKP39_08275) - 1677418..1677558 (+) 141 WP_326623864.1 hypothetical protein -
  VKP39_RS08280 (VKP39_08280) - 1677539..1677736 (+) 198 WP_326623865.1 hypothetical protein -
  VKP39_RS08285 (VKP39_08285) - 1677748..1678077 (+) 330 WP_111681410.1 hypothetical protein -
  VKP39_RS08290 (VKP39_08290) - 1678080..1678352 (+) 273 WP_001100459.1 hypothetical protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=840458 VKP39_RS08240 WP_003058809.1 1673238..1674005(-) (irvR) [Streptococcus pyogenes strain D641]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=840458 VKP39_RS08240 WP_003058809.1 1673238..1674005(-) (irvR) [Streptococcus pyogenes strain D641]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4