Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   VKP39_RS04765 Genome accession   NZ_CP142353
Coordinates   955456..955644 (-) Length   62 a.a.
NCBI ID   WP_011054546.1    Uniprot ID   A0A0H2UUN1
Organism   Streptococcus pyogenes strain D641     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 950456..960644
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP39_RS04740 (VKP39_04740) - 952256..952627 (+) 372 WP_002989617.1 GntR family transcriptional regulator -
  VKP39_RS04745 (VKP39_04745) - 952627..953325 (+) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  VKP39_RS04750 (VKP39_04750) - 953335..954120 (+) 786 WP_002984433.1 hypothetical protein -
  VKP39_RS04755 (VKP39_04755) - 954251..954865 (-) 615 WP_002989607.1 TVP38/TMEM64 family protein -
  VKP39_RS04765 (VKP39_04765) prx 955456..955644 (-) 189 WP_011054546.1 hypothetical protein Regulator
  VKP39_RS04770 (VKP39_04770) spel 955759..956547 (-) 789 WP_020833516.1 streptococcal pyrogenic exotoxin SpeL -
  VKP39_RS04775 (VKP39_04775) spem 956829..957542 (-) 714 WP_038431384.1 streptococcal pyrogenic exotoxin SpeM -
  VKP39_RS04780 (VKP39_04780) - 957846..958712 (-) 867 WP_326623567.1 hypothetical protein -
  VKP39_RS04785 (VKP39_04785) - 958700..959224 (-) 525 Protein_901 Panacea domain-containing protein -
  VKP39_RS04790 (VKP39_04790) - 959379..960131 (-) 753 WP_023611694.1 CHAP domain-containing protein -
  VKP39_RS04795 (VKP39_04795) - 960133..960465 (-) 333 WP_021733507.1 phage holin -

Sequence


Protein


Download         Length: 62 a.a.        Molecular weight: 7226.17 Da        Isoelectric Point: 3.9947

>NTDB_id=840418 VKP39_RS04765 WP_011054546.1 955456..955644(-) (prx) [Streptococcus pyogenes strain D641]
MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPHEEARNGEVVTEEKVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=840418 VKP39_RS04765 WP_011054546.1 955456..955644(-) (prx) [Streptococcus pyogenes strain D641]
ATGCTAACATACGACGAATTTAAGCAAGCTATTGATGACGGATATATCGTAGGAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAGGAAGCGAGAAATGGAGAAGTTGTGACAGAGGAGAAGGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2UUN1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1

  prx Streptococcus pyogenes MGAS315

84.746

95.161

0.806

  prx Streptococcus pyogenes MGAS8232

84.483

93.548

0.79

  prx Streptococcus pyogenes MGAS315

82.759

93.548

0.774

  prx Streptococcus pyogenes MGAS315

77.966

95.161

0.742

  prx Streptococcus pyogenes MGAS315

87.805

66.129

0.581

  prx Streptococcus pyogenes MGAS315

76.19

67.742

0.516