NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	VKP55_RS08585	Genome accession	NZ_CP142351
Coordinates	1719774..1720370 (-)	Length	198 a.a.
NCBI ID	WP_002992186.1	Uniprot ID	P0DF49
Organism	Streptococcus pyogenes strain SS1366
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1714774..1725370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP55_RS08550 (VKP55_08550)	-	1714835..1715140 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
VKP55_RS08555 (VKP55_08555)	ruvX	1715152..1715571 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
VKP55_RS08560 (VKP55_08560)	-	1715568..1715837 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
VKP55_RS08565 (VKP55_08565)	spx	1715951..1716349 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
VKP55_RS08570 (VKP55_08570)	recA	1716639..1717775 (-)	1137	WP_111705837.1	recombinase RecA	Machinery gene
VKP55_RS08575 (VKP55_08575)	cinA	1717864..1719135 (-)	1272	WP_326674187.1	competence/damage-inducible protein A	Machinery gene
VKP55_RS08580 (VKP55_08580)	-	1719204..1719764 (-)	561	WP_326674189.1	DNA-3-methyladenine glycosylase I	-
VKP55_RS08585 (VKP55_08585)	ruvA	1719774..1720370 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
VKP55_RS08590 (VKP55_08590)	-	1720372..1721592 (-)	1221	WP_002992187.1	MDR family MFS transporter	-
VKP55_RS08595 (VKP55_08595)	hexB	1721603..1723585 (-)	1983	WP_002992189.1	DNA mismatch repair endonuclease MutL	Machinery gene

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21879.26 Da Isoelectric Point: 6.8838

                                >NTDB_id=840263 VKP55_RS08585 WP_002992186.1 1719774..1720370(-) (ruvA) [Streptococcus pyogenes strain SS1366]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=840263 VKP55_RS08585 WP_002992186.1 1719774..1720370(-) (ruvA) [Streptococcus pyogenes strain SS1366]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.887	100	0.419

Detailed information NTG0840263