Detailed information
Bioinformatically predicted
Overview
| Name | comGH | Type | Machinery gene |
| Locus tag | VKP56_RS00685 | Genome accession | NZ_CP142350 |
| Coordinates | 105839..106792 (+) | Length | 317 a.a. |
| NCBI ID | WP_010921802.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain SS1445 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 100839..111792
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VKP56_RS00645 (VKP56_00645) | - | 101666..102031 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| VKP56_RS00650 (VKP56_00650) | comGA | 102124..103062 (+) | 939 | WP_326657116.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| VKP56_RS00655 (VKP56_00655) | comGB | 102998..104032 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| VKP56_RS00660 (VKP56_00660) | comGC | 104034..104360 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| VKP56_RS00665 (VKP56_00665) | comGD | 104335..104763 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| VKP56_RS00670 (VKP56_00670) | comGE | 104720..105004 (+) | 285 | WP_265415305.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| VKP56_RS00675 (VKP56_00675) | comGF | 104997..105431 (+) | 435 | WP_326657121.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| VKP56_RS00680 (VKP56_00680) | comGG | 105415..105741 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| VKP56_RS00685 (VKP56_00685) | comGH | 105839..106792 (+) | 954 | WP_010921802.1 | class I SAM-dependent methyltransferase | Machinery gene |
| VKP56_RS00690 (VKP56_00690) | - | 106851..108047 (+) | 1197 | WP_011284424.1 | acetate kinase | - |
| VKP56_RS00695 (VKP56_00695) | - | 108234..108542 (+) | 309 | WP_030126458.1 | hypothetical protein | - |
| VKP56_RS00700 (VKP56_00700) | proC | 108625..109395 (-) | 771 | WP_014407219.1 | pyrroline-5-carboxylate reductase | - |
| VKP56_RS00705 (VKP56_00705) | pepA | 109443..110510 (-) | 1068 | WP_115353942.1 | glutamyl aminopeptidase | - |
| VKP56_RS00710 (VKP56_00710) | - | 110975..111259 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| VKP56_RS00715 (VKP56_00715) | - | 111256..111573 (+) | 318 | WP_002986515.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36015.10 Da Isoelectric Point: 4.7205
>NTDB_id=840093 VKP56_RS00685 WP_010921802.1 105839..106792(+) (comGH) [Streptococcus pyogenes strain SS1445]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=840093 VKP56_RS00685 WP_010921802.1 105839..106792(+) (comGH) [Streptococcus pyogenes strain SS1445]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGH | Streptococcus mutans UA159 |
65.823 |
99.685 |
0.656 |
| comGH | Streptococcus mutans UA140 |
65.506 |
99.685 |
0.653 |