NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	VKP35_RS08985	Genome accession	NZ_CP142349
Coordinates	1758571..1759167 (-)	Length	198 a.a.
NCBI ID	WP_002982180.1	Uniprot ID	-
Organism	Streptococcus pyogenes strain 11RS100
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1753571..1764167

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP35_RS08950 (VKP35_08950)	-	1753632..1753937 (-)	306	WP_326622826.1	DUF1292 domain-containing protein	-
VKP35_RS08955 (VKP35_08955)	ruvX	1753949..1754368 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
VKP35_RS08960 (VKP35_08960)	-	1754365..1754634 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
VKP35_RS08965 (VKP35_08965)	spx	1754747..1755145 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
VKP35_RS08970 (VKP35_08970)	recA	1755436..1756572 (-)	1137	WP_326622828.1	recombinase RecA	Machinery gene
VKP35_RS08975 (VKP35_08975)	cinA	1756661..1757932 (-)	1272	WP_111713422.1	competence/damage-inducible protein A	Machinery gene
VKP35_RS08980 (VKP35_08980)	-	1758001..1758561 (-)	561	WP_023611248.1	DNA-3-methyladenine glycosylase I	-
VKP35_RS08985 (VKP35_08985)	ruvA	1758571..1759167 (-)	597	WP_002982180.1	Holliday junction branch migration protein RuvA	Machinery gene
VKP35_RS08990 (VKP35_08990)	-	1759169..1760389 (-)	1221	WP_002982178.1	MDR family MFS transporter	-
VKP35_RS08995 (VKP35_08995)	hexB	1760400..1762382 (-)	1983	WP_011018317.1	DNA mismatch repair endonuclease MutL	Machinery gene
VKP35_RS09000 (VKP35_09000)	-	1762477..1763622 (-)	1146	WP_021775554.1	tyrosine-type recombinase/integrase	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21829.16 Da Isoelectric Point: 6.2537

                                >NTDB_id=840074 VKP35_RS08985 WP_002982180.1 1758571..1759167(-) (ruvA) [Streptococcus pyogenes strain 11RS100]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL

LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=840074 VKP35_RS08985 WP_002982180.1 1758571..1759167(-) (ruvA) [Streptococcus pyogenes strain 11RS100]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA

CATCAAATCAGCCCTTAAACTGTTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	66.497	99.495	0.662
ruvA	Streptococcus pneumoniae R6	66.497	99.495	0.662
ruvA	Streptococcus pneumoniae D39	66.497	99.495	0.662
ruvA	Bacillus subtilis subsp. subtilis str. 168	41.379	100	0.424

Detailed information NTG0840074