Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   VKP35_RS05615 Genome accession   NZ_CP142349
Coordinates   1105387..1105575 (-) Length   62 a.a.
NCBI ID   WP_011054546.1    Uniprot ID   A0A0H2UUN1
Organism   Streptococcus pyogenes strain 11RS100     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context

Location: 1100387..1110575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP35_RS05590 (VKP35_05590) - 1102187..1102558 (+) 372 WP_002989617.1 GntR family transcriptional regulator -
  VKP35_RS05595 (VKP35_05595) - 1102558..1103256 (+) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  VKP35_RS05600 (VKP35_05600) - 1103266..1104051 (+) 786 WP_002984433.1 hypothetical protein -
  VKP35_RS05605 (VKP35_05605) - 1104182..1104796 (-) 615 WP_002989607.1 TVP38/TMEM64 family protein -
  VKP35_RS05615 (VKP35_05615) prx 1105387..1105575 (-) 189 WP_011054546.1 hypothetical protein Regulator
  VKP35_RS05620 (VKP35_05620) spel 1105690..1106478 (-) 789 WP_020833516.1 streptococcal pyrogenic exotoxin SpeL -
  VKP35_RS05625 (VKP35_05625) spem 1106760..1107473 (-) 714 WP_014635497.1 streptococcal pyrogenic exotoxin SpeM -
  VKP35_RS05630 (VKP35_05630) - 1107777..1108643 (-) 867 WP_014635498.1 DUF334 domain-containing protein -
  VKP35_RS05635 (VKP35_05635) - 1108631..1109155 (-) 525 WP_011017840.1 Panacea domain-containing protein -
  VKP35_RS05640 (VKP35_05640) - 1109295..1110503 (-) 1209 WP_326622395.1 glucosaminidase domain-containing protein -

Sequence

Protein


Download         Length: 62 a.a.        Molecular weight: 7226.17 Da        Isoelectric Point: 3.9947

>NTDB_id=840047 VKP35_RS05615 WP_011054546.1 1105387..1105575(-) (prx) [Streptococcus pyogenes strain 11RS100]
MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPHEEARNGEVVTEEKVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=840047 VKP35_RS05615 WP_011054546.1 1105387..1105575(-) (prx) [Streptococcus pyogenes strain 11RS100]
ATGCTAACATACGACGAATTTAAGCAAGCTATTGATGACGGATATATCGTAGGAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAGGAAGCGAGAAATGGAGAAGTTGTGACAGAGGAGAAGGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UUN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1
  prx Streptococcus pyogenes MGAS315

84.746

95.161

0.806
  prx Streptococcus pyogenes MGAS8232

84.483

93.548

0.79
  prx Streptococcus pyogenes MGAS315

82.759

93.548

0.774
  prx Streptococcus pyogenes MGAS315

77.966

95.161

0.742
  prx Streptococcus pyogenes MGAS315

87.805

66.129

0.581
  prx Streptococcus pyogenes MGAS315

76.19

67.742

0.516