Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   VOI49_RS10180 Genome accession   NZ_CP142018
Coordinates   2026552..2028534 (-) Length   660 a.a.
NCBI ID   WP_226313900.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain lu24     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2021552..2033534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS10155 cinA 2022393..2023664 (-) 1272 WP_226313886.1 competence/damage-inducible protein A Machinery gene
  VOI49_RS10160 - 2023860..2024144 (-) 285 WP_226313887.1 VOC family protein -
  VOI49_RS10165 - 2024144..2024716 (-) 573 WP_115253192.1 DNA-3-methyladenine glycosylase I -
  VOI49_RS10170 ruvA 2024726..2025319 (-) 594 WP_226313888.1 Holliday junction branch migration protein RuvA Machinery gene
  VOI49_RS10175 - 2025321..2026541 (-) 1221 WP_226313889.1 MDR family MFS transporter -
  VOI49_RS10180 hexB 2026552..2028534 (-) 1983 WP_226313900.1 DNA mismatch repair endonuclease MutL Machinery gene
  VOI49_RS10185 - 2029818..2033132 (+) 3315 WP_324739005.1 serum opacification factor -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74477.94 Da        Isoelectric Point: 5.2983

>NTDB_id=839237 VOI49_RS10180 WP_226313900.1 2026552..2028534(-) (hexB) [Streptococcus dysgalactiae strain lu24]
MSKIIELPEILANQIAAGEVVERPASVVKELVENAIDAKSSQITIDIEESGLKMIEITDNGEGMSSEDLPLSLRRHATSK
IKTQSDLFRIRTLGFRGEALPSVASISKITIKTATKEAAYGSLLIATGGEIETLEETPTPVGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEIAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIPISSADLDFEVSGYVSLP
ELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALESLAKSSTRHFSKPEQTQLPLQSKGLYYDPQKNDFFVKESDVSEKLPESNFHDTEIDKTVKDQR
TEQFPDLGENTGFSSVKRASRSQDEVTDADHPGFDLKNKQKLSQMLTRLENEERSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=839237 VOI49_RS10180 WP_226313900.1 2026552..2028534(-) (hexB) [Streptococcus dysgalactiae strain lu24]
ATATCAAAAATTATTGAATTACCAGAAATTCTCGCTAACCAAATTGCAGCGGGTGAAGTTGTAGAAAGGCCAGCTAGTGT
TGTCAAGGAATTAGTTGAAAATGCTATTGATGCAAAAAGTAGTCAGATTACTATTGACATTGAAGAGTCAGGTCTCAAAA
TGATAGAAATTACAGACAATGGTGAAGGGATGTCATCTGAAGATCTCCCTTTGAGCTTGCGGCGACATGCTACCAGTAAA
ATCAAAACTCAGAGTGATCTCTTTCGCATTAGAACGCTTGGTTTTAGGGGAGAAGCTTTACCATCGGTTGCTTCTATCAG
CAAAATTACGATAAAAACAGCTACTAAGGAAGCTGCTTATGGCTCTCTACTAATTGCAACTGGTGGAGAGATTGAAACGC
TCGAGGAAACGCCGACGCCTGTAGGTACTAAGATTAAGGTTGAAAACCTTTTTTATAATACACCTGCTCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAGTTAGCTCATATTGTTGATGTGGTTAATCGTTTGAGTTTGGCTCATCCAGAAATTGCTTT
CACCCTGATTAGTGATGGCCGTCAATTAACTCAGACGTCAGGGACGGGAGATCTTCGGCAGGCTATTGCGGGCATTTATG
GCTTGAATACTGCGAAGAAAATGATTCCTATTTCCAGTGCTGATTTGGACTTTGAAGTGTCGGGCTATGTCAGTTTACCA
GAGTTGACACGCGCCAACCGCAATTATATGACGATTTTAGTCAATGGACGCTACATTAAAAATTTCTTGCTCAATCGGGC
TATTTTAGATGGTTATGGCTCTAAGTTGATGGTTGGACGTTTCCCAATTGTGGTGATTGATATTCAGATTGACCCCTATT
TGGCCGATGTCAATGTTCACCCTACTAAGCAAGAGGTCCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATTAGTACG
GCGATTTCTGAAAGTCTTAAGGAGCAAGATTTGATTCCAGATGCTCTGGAGAGCTTAGCTAAATCAAGCACACGACACTT
TTCTAAACCAGAGCAAACACAACTTCCATTACAATCTAAAGGGCTTTATTATGATCCTCAAAAGAATGATTTTTTTGTCA
AAGAATCAGACGTTTCTGAAAAACTGCCTGAGAGTAATTTTCATGATACAGAGATTGACAAGACTGTAAAGGATCAAAGG
ACGGAGCAGTTTCCTGATTTAGGAGAGAATACAGGATTTTCCTCAGTAAAACGTGCTAGTCGATCACAGGATGAGGTAAC
TGATGCTGATCACCCTGGATTTGATTTGAAAAACAAACAGAAATTATCTCAAATGCTAACCCGTTTGGAAAATGAAGAGC
GATCGGTATTTCCTGAATTGGATTATTTTGGTCAGATGCACGGCACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATAGGTGAAGTTGACAGTAGTTT
ACAGCAATTGTTGGTGCCCTATTTGTTTGAGTTTTCCGGCTCGGATTTCATTAATTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGCATCTTTCTGGAAGTGTATGGGCACAATACTTTCATCTTGAGGGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTATCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTGC
TGCAATTGGCGCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTATTGATTAATTTCAGTAAAGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCATACTAGCCTGCGAGAACTAGGAAAATATTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

MutL C terminal dimerisation domain (MutL_C)

(462-604)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

67.523

100

0.677