Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   U0450_RS07610 Genome accession   NZ_CP139863
Coordinates   1484031..1484690 (-) Length   219 a.a.
NCBI ID   WP_000565010.1    Uniprot ID   Q8DNN1
Organism   Streptococcus pneumoniae strain 15P2112     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1479031..1489690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS07580 - 1479211..1479810 (+) 600 WP_050233567.1 phosphoribosylanthranilate isomerase -
  U0450_RS07585 trpB 1479788..1481011 (+) 1224 WP_000331288.1 tryptophan synthase subunit beta -
  U0450_RS07590 trpA 1481004..1481780 (+) 777 WP_001127010.1 tryptophan synthase subunit alpha -
  U0450_RS07595 - 1481752..1481856 (-) 105 Protein_1451 prepilin peptidase -
  U0450_RS07600 - 1482082..1482813 (+) 732 Protein_1452 hypothetical protein -
  U0450_RS07605 - 1482828..1483979 (+) 1152 WP_000481756.1 XRE family transcriptional regulator -
  U0450_RS07610 cclA/cilC 1484031..1484690 (-) 660 WP_000565010.1 A24 family peptidase Machinery gene
  U0450_RS07615 - 1484760..1485158 (+) 399 WP_127245082.1 N-acetyltransferase -
  U0450_RS07620 - 1485434..1486612 (-) 1179 WP_001866460.1 ROK family transcriptional regulator -
  U0450_RS07625 - 1486892..1488154 (+) 1263 WP_127245081.1 PTS sugar transporter subunit IIC -
  U0450_RS07630 - 1488157..1489053 (+) 897 WP_000825669.1 PEP phosphonomutase -
  U0450_RS07635 - 1489068..1489385 (+) 318 WP_001151646.1 PTS sugar transporter subunit IIB -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24845.99 Da        Isoelectric Point: 7.5762

>NTDB_id=832472 U0450_RS07610 WP_000565010.1 1484031..1484690(-) (cclA/cilC) [Streptococcus pneumoniae strain 15P2112]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=832472 U0450_RS07610 WP_000565010.1 1484031..1484690(-) (cclA/cilC) [Streptococcus pneumoniae strain 15P2112]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGTAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DNN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

100

100

1
  cclA/cilC Streptococcus pneumoniae D39

100

100

1
  cclA/cilC Streptococcus pneumoniae R6

100

100

1
  cclA/cilC Streptococcus pneumoniae TIGR4

94.977

100

0.95
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877