Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   U0447_RS03140 Genome accession   NZ_CP139861
Coordinates   608461..609120 (+) Length   219 a.a.
NCBI ID   WP_000565023.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 603461..614120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS03115 - 603766..604083 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  U0447_RS03120 - 604098..604994 (-) 897 WP_001865114.1 hypothetical protein -
  U0447_RS03125 - 604997..606259 (-) 1263 WP_000413342.1 PTS sugar transporter subunit IIC -
  U0447_RS03130 - 606539..607717 (+) 1179 WP_000175880.1 ROK family transcriptional regulator -
  U0447_RS03135 - 607945..608391 (-) 447 WP_000155406.1 GNAT family N-acetyltransferase -
  U0447_RS03140 cclA/cilC 608461..609120 (+) 660 WP_000565023.1 A24 family peptidase Machinery gene
  U0447_RS03145 - 609172..610323 (-) 1152 WP_000481750.1 ImmA/IrrE family metallo-endopeptidase -
  U0447_RS03150 - 610338..611069 (-) 732 WP_000934017.1 hypothetical protein -
  U0447_RS03155 - 611295..611399 (+) 105 Protein_622 prepilin peptidase -
  U0447_RS03160 trpA 611371..612147 (-) 777 WP_001127010.1 tryptophan synthase subunit alpha -
  U0447_RS03165 trpB 612140..613363 (-) 1224 WP_000331292.1 tryptophan synthase subunit beta -
  U0447_RS03170 - 613341..613940 (-) 600 WP_000169898.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24921.13 Da        Isoelectric Point: 8.2409

>NTDB_id=832173 U0447_RS03140 WP_000565023.1 608461..609120(+) (cclA/cilC) [Streptococcus pneumoniae strain 16H2017-2]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=832173 U0447_RS03140 WP_000565023.1 608461..609120(+) (cclA/cilC) [Streptococcus pneumoniae strain 16H2017-2]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTTCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae Rx1

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae D39

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae R6

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

86.301

100

0.863