Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   OPT60_RS03090 Genome accession   NZ_CP125359
Coordinates   574252..575604 (+) Length   450 a.a.
NCBI ID   WP_084916257.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain UT_10236     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 569252..580604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OPT60_RS03065 (OPT60_03065) - 570319..570966 (-) 648 WP_003057245.1 amino acid ABC transporter permease -
  OPT60_RS03070 (OPT60_03070) - 570981..571682 (-) 702 WP_003057191.1 amino acid ABC transporter permease -
  OPT60_RS03075 (OPT60_03075) - 571696..572496 (-) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  OPT60_RS03080 (OPT60_03080) - 572496..573290 (-) 795 WP_084916254.1 amino acid ABC transporter ATP-binding protein -
  OPT60_RS03085 (OPT60_03085) vicR 573549..574259 (+) 711 WP_084916255.1 response regulator YycF Regulator
  OPT60_RS03090 (OPT60_03090) vicK 574252..575604 (+) 1353 WP_084916257.1 cell wall metabolism sensor histidine kinase VicK Regulator
  OPT60_RS03095 (OPT60_03095) vicX 575608..576417 (+) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  OPT60_RS03100 (OPT60_03100) rnc 577175..577867 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51550.14 Da        Isoelectric Point: 5.5741

>NTDB_id=831213 OPT60_RS03090 WP_084916257.1 574252..575604(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain UT_10236]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSYKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKFYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=831213 OPT60_RS03090 WP_084916257.1 574252..575604(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain UT_10236]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCTATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAAGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACGCCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTTATCAAGGTTTCTCTTGATGAAACTAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGTTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-165)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

72.947

92

0.671
  micB Streptococcus pneumoniae Cp1015

66.588

94.444

0.629