Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   R8559_RS10060 Genome accession   NZ_AP026926
Coordinates   1921668..1921934 (-) Length   88 a.a.
NCBI ID   WP_050123149.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700119     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1916668..1926934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8559_RS10015 (PC0116_19550) rnpA 1916692..1917063 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8559_RS10020 - 1917080..1917211 (-) 132 WP_000768903.1 hypothetical protein -
  R8559_RS10025 (PC0116_19560) - 1917212..1918402 (-) 1191 WP_000167759.1 acetate kinase -
  R8559_RS10030 (PC0116_19570) comGH 1918453..1919406 (-) 954 WP_000345123.1 class I SAM-dependent methyltransferase Machinery gene
  R8559_RS10035 (PC0116_19580) - 1919467..1920054 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  R8559_RS10040 (PC0116_19590) comGG/cglG 1920191..1920604 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8559_RS10045 (PC0116_19600) comGF/cglF 1920582..1921043 (-) 462 WP_000250548.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8559_RS10050 (PC0116_19610) comGE/cglE 1921006..1921308 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8559_RS10055 (PC0116_19620) comGD/cglD 1921271..1921675 (-) 405 WP_000588007.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8559_RS10060 (PC0116_19630) comGC/cglC 1921668..1921934 (-) 267 WP_050123149.1 competence type IV pilus major pilin ComGC Machinery gene
  R8559_RS10065 (PC0116_19640) - 1921936..1922193 (-) 258 WP_000698513.1 hypothetical protein -
  R8559_RS10070 (PC0116_19650) - 1922463..1923419 (-) 957 WP_317639174.1 N-acetylmuramoyl-L-alanine amidase family protein -
  R8559_RS10075 (PC0116_19660) - 1923422..1923757 (-) 336 WP_050200954.1 phage holin -
  R8559_RS10080 (PC0116_19670) - 1923761..1924060 (-) 300 WP_001811580.1 hypothetical protein -
  R8559_RS10085 (PC0116_19680) - 1924069..1924419 (-) 351 WP_221014204.1 hypothetical protein -
  R8559_RS10090 (PC0116_19690) - 1924422..1924625 (-) 204 WP_001091118.1 hypothetical protein -
  R8559_RS10095 - 1924606..1924722 (-) 117 WP_001063633.1 hypothetical protein -

Sequence


Protein


Download         Length: 88 a.a.        Molecular weight: 9872.39 Da        Isoelectric Point: 6.3582

>NTDB_id=82855 R8559_RS10060 WP_050123149.1 1921668..1921934(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700119]
MLVVLLIISVLFLLFVPNLAKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNV
GANRKVYD

Nucleotide


Download         Length: 267 bp        

>NTDB_id=82855 R8559_RS10060 WP_050123149.1 1921668..1921934(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700119]
ATGTTGGTGGTCTTGCTGATTATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGGCCAAGCAAAAAGAAGCAGTCAA
TGACAAAGGAAAAGCAGCTGTTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTA
GCCTAAGCAAGTTAAAAGAAGATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACAATGATAAAAATGTA
GGAGCAAATCGTAAAGTCTATGATTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

93.182

100

0.932

  comGC/cglC Streptococcus pneumoniae Rx1

92.045

100

0.92

  comGC/cglC Streptococcus pneumoniae D39

92.045

100

0.92

  comGC/cglC Streptococcus pneumoniae R6

92.045

100

0.92

  comGC/cglC Streptococcus mitis SK321

87.838

84.091

0.739

  comGC/cglC Streptococcus mitis NCTC 12261

90.625

72.727

0.659

  comGC Streptococcus gordonii str. Challis substr. CH1

70

90.909

0.636

  comGC Streptococcus suis isolate S10

65.278

81.818

0.534

  comGC Streptococcus mutans UA140

58.571

79.545

0.466

  comGC Streptococcus mutans UA159

58.571

79.545

0.466

  comGC Lactococcus lactis subsp. cremoris KW2

50.667

85.227

0.432

  comGC Staphylococcus aureus MW2

47.826

78.409

0.375

  comGC Staphylococcus aureus N315

47.826

78.409

0.375


Multiple sequence alignment