Detailed information NTG0082855

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: H7676_RS06545
• Genome accession: NZ_AP023390
• Coordinates: 1337015..1337740 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain KUN-0014944
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1332015..1342740

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7676_RS06510 (KUN4944_12400)	rnpM	1332049..1332345 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
H7676_RS06515 (KUN4944_12410)	nusA	1332361..1333518 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
H7676_RS06520 (KUN4944_12420)	rimP	1333693..1334229 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
H7676_RS06530 (KUN4944_12430)	trmB	1334488..1335123 (-)	636	WP_031488472.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
H7676_RS06535 (KUN4944_12440)	ccrZ	1335123..1335914 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
H7676_RS06540 (KUN4944_12450)	-	1335978..1337012 (-)	1035	WP_031577431.1	ABC transporter permease	-
H7676_RS06545 (KUN4944_12460)	pptA	1337015..1337740 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
H7676_RS06550 (KUN4944_12470)	-	1337812..1338231 (+)	420	WP_002983376.1	HIT family protein	-
H7676_RS06555 (KUN4944_12480)	-	1338228..1338584 (+)	357	WP_031488470.1	hypothetical protein	-
H7676_RS06560 (KUN4944_12490)	brpA	1338695..1339978 (-)	1284	WP_031488469.1	biofilm formation/cell division transcriptional regulator BrpA	-
H7676_RS06565 (KUN4944_12500)	-	1339987..1340511 (-)	525	WP_031488468.1	GNAT family N-acetyltransferase	-
H7676_RS06570 (KUN4944_12510)	tsaE	1340486..1340947 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
H7676_RS06575 (KUN4944_12520)	-	1341101..1342561 (-)	1461	WP_031488467.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=82855 H7676_RS06545 WP_002983379.1 1337015..1337740(-) (pptA) [Streptococcus pyogenes strain KUN-0014944]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=82855 H7676_RS06545 WP_002983379.1 1337015..1337740(-) (pptA) [Streptococcus pyogenes strain KUN-0014944]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714