Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R4710_RS04850 Genome accession   NZ_CP137101
Coordinates   898905..899345 (-) Length   146 a.a.
NCBI ID   WP_001206581.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 893905..904345
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS04820 - 894207..895082 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  R4710_RS04825 pstC 895200..896063 (+) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  R4710_RS04830 pstA 896056..896871 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  R4710_RS04835 pstB 896873..897625 (+) 753 WP_000536447.1 phosphate ABC transporter ATP-binding protein PstB -
  R4710_RS04840 phoU 897640..898290 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  R4710_RS04845 - 898339..898782 (+) 444 Protein_912 transposase -
  R4710_RS04850 comR 898905..899345 (-) 441 WP_001206581.1 helix-turn-helix transcriptional regulator Regulator
  R4710_RS04855 - 899557..900573 (+) 1017 WP_000415110.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  R4710_RS04860 galU 900595..901494 (+) 900 WP_000202228.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  R4710_RS04865 - 901561..902238 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  R4710_RS04870 - 902222..902761 (-) 540 WP_000834311.1 5-formyltetrahydrofolate cyclo-ligase -
  R4710_RS04875 - 902773..903903 (-) 1131 WP_000885068.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17728.46 Da        Isoelectric Point: 4.8659

>NTDB_id=818565 R4710_RS04850 WP_001206581.1 898905..899345(-) (comR) [Streptococcus pneumoniae strain 16P2012-2]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYF
LMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 441 bp        

>NTDB_id=818565 R4710_RS04850 WP_001206581.1 898905..899345(-) (comR) [Streptococcus pneumoniae strain 16P2012-2]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTG
AACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCCTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTA
TTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTAGCACTAGCGAACTACACAGTTCAAA
AATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(72-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55

82.192

0.452
  comR Streptococcus pyogenes MGAS315

53.333

82.192

0.438
  comR Streptococcus mutans UA159

51.667

82.192

0.425
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

53.636

75.342

0.404
  comR Streptococcus suis P1/7

46.61

80.822

0.377
  comR Streptococcus suis 05ZYH33

46.61

80.822

0.377
  comR Streptococcus suis D9

45.763

80.822

0.37
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

46.491

78.082

0.363