Detailed information NTG0815946

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY59_RS10670
• Genome accession: NZ_CP122487
• Coordinates: 2101312..2102199 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain IT-MRSA45
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2096312..2107199

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY59_RS10640 (QAY59_10630)	-	2096331..2096423 (+)	93	WP_010956583.1	hypothetical protein	-
QAY59_RS10645 (QAY59_10635)	-	2096531..2097028 (-)	498	WP_001065268.1	glutathione peroxidase	-
QAY59_RS10650 (QAY59_10640)	-	2097038..2097298 (-)	261	WP_001791974.1	hypothetical protein	-
QAY59_RS10655 (QAY59_10645)	-	2097680..2097793 (-)	114	Protein_2071	hypothetical protein	-
QAY59_RS10660 (QAY59_10650)	-	2098452..2100452 (-)	2001	WP_000776740.1	ABC transporter permease	-
QAY59_RS10665 (QAY59_10655)	-	2100449..2101204 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAY59_RS10670 (QAY59_10660)	braS	2101312..2102199 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY59_RS10675 (QAY59_10665)	braR	2102210..2102875 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY59_RS10680 (QAY59_10670)	-	2102901..2103101 (-)	201	WP_000604727.1	hypothetical protein	-
QAY59_RS10685 (QAY59_10675)	-	2103299..2104723 (+)	1425	WP_000953748.1	alkaline phosphatase	-
QAY59_RS10690	-	2104783..2104884 (-)	102	WP_000731972.1	SE2200 family small protein	-
QAY59_RS10695 (QAY59_10685)	-	2105006..2105461 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY59_RS10700 (QAY59_10690)	-	2105706..2106467 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=815946 QAY59_RS10670 WP_000143417.1 2101312..2102199(-) (braS) [Staphylococcus aureus strain IT-MRSA45]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=815946 QAY59_RS10670 WP_000143417.1 2101312..2102199(-) (braS) [Staphylococcus aureus strain IT-MRSA45]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99