NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	P5649_RS08280	Genome accession	NZ_CP120613
Coordinates	1609468..1610061 (-)	Length	197 a.a.
NCBI ID	WP_003228214.1	Uniprot ID	A0A199WEF2
Organism	Bacillus subtilis strain DSM 23521
Function	degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1604468..1615061

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P5649_RS08265 (P5649_08265)	mdxK	1604794..1607067 (+)	2274	WP_003243769.1	maltose phosphorylase	-
P5649_RS08270 (P5649_08270)	malL	1607060..1608745 (+)	1686	WP_003243333.1	oligo-1,6-glucosidase	-
P5649_RS08275 (P5649_08275)	pgmB	1608742..1609422 (+)	681	WP_003228210.1	beta-phosphoglucomutase	-
P5649_RS08280 (P5649_08280)	clpP	1609468..1610061 (-)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
P5649_RS08290 (P5649_08290)	cotR	1610691..1611653 (-)	963	WP_003243674.1	sporulation hydrolase CotR	-
P5649_RS08295 (P5649_08295)	cotNP	1612009..1613352 (+)	1344	WP_003228217.1	FAD-binding oxidoreductase	-
P5649_RS08300 (P5649_08300)	yvdQ	1613604..1614116 (+)	513	WP_003243249.1	DUF3231 family protein	-
P5649_RS08305 (P5649_08305)	psmB	1614152..1614472 (-)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
P5649_RS08310 (P5649_08310)	psmA	1614472..1614808 (-)	337	Protein_1603	SMR family transporter	-

Sequence

Protein

Download Length: 197 a.a. Molecular weight: 21682.00 Da Isoelectric Point: 4.9416

                                >NTDB_id=806899 P5649_RS08280 WP_003228214.1 1609468..1610061(-) (clpP) [Bacillus subtilis strain DSM 23521]

MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT

MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ

PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

Download Length: 594 bp

                                >NTDB_id=806899 P5649_RS08280 WP_003228214.1 1609468..1610061(-) (clpP) [Bacillus subtilis strain DSM 23521]

ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA

TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG

AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC

ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG

CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAAGCGA

CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG

CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA

CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A199WEF2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538

Detailed information NTG0806899