Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   RJW53_RS07770 Genome accession   NZ_CP134488
Coordinates   1521621..1522970 (-) Length   449 a.a.
NCBI ID   WP_074392660.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS50     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1516621..1527970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW53_RS07750 (RJW53_07750) recR 1517319..1517915 (-) 597 WP_002935848.1 recombination mediator RecR Machinery gene
  RJW53_RS07755 (RJW53_07755) pbp2b 1517924..1519999 (-) 2076 WP_024405652.1 penicillin-binding protein PBP2B -
  RJW53_RS07760 (RJW53_07760) - 1520091..1520465 (-) 375 WP_023369696.1 ATP-binding cassette domain-containing protein -
  RJW53_RS07765 (RJW53_07765) vicX 1520811..1521614 (-) 804 WP_023369694.1 MBL fold metallo-hydrolase Regulator
  RJW53_RS07770 (RJW53_07770) micB 1521621..1522970 (-) 1350 WP_074392660.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RJW53_RS07775 (RJW53_07775) yycF 1522963..1523667 (-) 705 WP_002935840.1 response regulator YycF -
  RJW53_RS07780 (RJW53_07780) - 1523888..1525609 (+) 1722 WP_074389404.1 IS1634 family transposase -
  RJW53_RS07785 (RJW53_07785) - 1525850..1526611 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  RJW53_RS07790 (RJW53_07790) - 1526622..1527461 (+) 840 WP_029752656.1 transporter substrate-binding domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51065.11 Da        Isoelectric Point: 4.4860

>NTDB_id=804117 RJW53_RS07770 WP_074392660.1 1521621..1522970(-) (micB) [Streptococcus suis strain NLS50]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGYGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=804117 RJW53_RS07770 WP_074392660.1 1521621..1522970(-) (micB) [Streptococcus suis strain NLS50]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTTGTCGTCTTGCATGATATGACCGAGCAAGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTAT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTCAAGGTATCCTTGGATGAGACCAACCGCATGATGCGGATGATTACAGATCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTTATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635