Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   RJW53_RS01250 Genome accession   NZ_CP134488
Coordinates   227526..229859 (+) Length   777 a.a.
NCBI ID   WP_024405878.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS50     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 222526..234859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW53_RS01230 (RJW53_01230) treP 223177..225171 (-) 1995 WP_074389710.1 PTS system trehalose-specific EIIBC component -
  RJW53_RS01235 (RJW53_01235) treR 225404..226117 (+) 714 WP_024393394.1 trehalose operon repressor Regulator
  RJW53_RS01240 (RJW53_01240) - 226175..226486 (+) 312 WP_002935948.1 hypothetical protein -
  RJW53_RS01245 (RJW53_01245) - 226483..227031 (+) 549 WP_002935945.1 CvpA family protein -
  RJW53_RS01250 (RJW53_01250) mutS/mutS2 227526..229859 (+) 2334 WP_024405878.1 endonuclease MutS2 Machinery gene
  RJW53_RS01255 (RJW53_01255) - 229883..230595 (+) 713 Protein_215 GNAT family N-acetyltransferase -
  RJW53_RS01260 (RJW53_01260) trxA 230960..231274 (+) 315 WP_024386049.1 thioredoxin -
  RJW53_RS11800 - 231374..231424 (-) 51 WP_353735889.1 hypothetical protein -
  RJW53_RS01265 (RJW53_01265) - 231414..232943 (+) 1530 WP_074389711.1 AMP-binding protein -
  RJW53_RS01270 (RJW53_01270) msrB 232983..233921 (+) 939 WP_074389391.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 777 a.a.        Molecular weight: 87597.32 Da        Isoelectric Point: 6.5651

>NTDB_id=804075 RJW53_RS01250 WP_024405878.1 227526..229859(+) (mutS/mutS2) [Streptococcus suis strain NLS50]
MNNKIIETLEFHKVRQKIEPYLLTEQGFEELRQLEPMVEVHRIQQAFDELTDIAQIFVENPYFSLAATSDIGPAMRRLEL
DTDLNIAELLAVKKVLEVSKSLLDFYGNLENVSLSQLDKLFEKIELFPHLQGSLQSINDAGFVEDFASEKLARIRRKIRE
AEDQVRQVMQDILKTKGDMLSDSILASRNGRNVLPVKNTYRNKIAGVVHDISASGSTVYIEPRAVVTLNEEISHLRAEER
HELNRILQELSDMLRPHSGVIRNNAWLIGHIDFVRAKHLFARDHQAVVPKLSEKQDIALLNVRHPLIAKPVPNDLYFGSQ
LTAIVITGPNTGGKTIMLKTLGLTHLMAQSGLPILADEGSRVAIFKEIFADIGDEQSIEQSLSTFSSHMTHTVEILRAAD
QDSLILFDELGAGTDPQEGASLAMAILDDLRLRGIKTMATTHYPELKAYGIETSGIENASMEFDSNSLRPTYKFMQGVPG
RSNAFEIARRLGLSDIIIQSAQSWTDTDSDVNRIIEKLESQTVESRQRLDKIRDVEQENYKMNRALRKLYDELNRERENE
LNKARLEAKEIVDMALAESEDILKNLHAAASLKPHQIIEAKAELKKLAPEVVDLSKNKVLKKAKIQREAKVGDDIIVTAY
GQRGTLTNQLKDGRWEAQVGLIKMTLAKDEFELVKAEKAEQPKKRQVHTVKRANVRGPKARLDLRGKRYEEAMMELDEFI
DQALLNNLAQVDIVHGIGTGVIREGVTKYLRRNKQVKEFGYAPQNAGGSGCTIVMFK

Nucleotide


Download         Length: 2334 bp        

>NTDB_id=804075 RJW53_RS01250 WP_024405878.1 227526..229859(+) (mutS/mutS2) [Streptococcus suis strain NLS50]
ATGAATAATAAAATTATTGAAACCCTTGAATTTCACAAGGTAAGACAAAAAATTGAGCCCTATCTCTTGACGGAACAGGG
CTTTGAAGAATTACGACAGTTGGAGCCCATGGTGGAAGTCCATCGTATCCAACAGGCCTTCGACGAGTTGACAGACATAG
CGCAGATTTTTGTGGAAAATCCCTATTTCAGTCTGGCTGCTACTAGTGACATCGGTCCAGCCATGCGTCGTTTGGAATTG
GATACAGACCTCAATATCGCTGAATTATTAGCTGTTAAAAAGGTCTTGGAAGTTTCTAAATCTCTCTTGGATTTTTATGG
AAATCTGGAAAATGTCAGTCTTAGCCAGTTGGATAAACTCTTTGAGAAGATTGAGCTTTTTCCACATTTACAGGGCTCCC
TCCAGTCCATCAATGATGCTGGTTTTGTAGAGGATTTTGCCTCAGAAAAGCTGGCTCGTATTCGAAGAAAAATCCGTGAA
GCTGAAGATCAAGTTCGTCAGGTCATGCAGGATATTTTGAAGACCAAGGGCGACATGCTGTCCGATAGCATTTTGGCAAG
CCGTAATGGACGCAATGTCCTTCCTGTTAAAAATACCTATCGCAATAAGATTGCAGGGGTTGTCCATGACATTTCAGCTT
CGGGTTCGACCGTTTATATTGAGCCGCGGGCAGTGGTGACCTTGAACGAAGAAATCAGTCACCTACGTGCAGAAGAACGC
CATGAGCTCAACCGTATCTTGCAGGAATTGTCGGATATGCTCCGTCCGCATAGTGGCGTGATTCGTAACAATGCCTGGCT
TATCGGACATATTGATTTCGTCCGTGCTAAGCATCTCTTTGCGCGTGATCATCAAGCAGTTGTACCCAAACTATCTGAGA
AGCAGGATATTGCCCTTCTCAACGTTCGGCATCCGCTCATTGCTAAGCCTGTACCAAATGACCTTTATTTCGGTAGTCAG
TTGACGGCTATCGTGATAACAGGTCCCAACACAGGTGGTAAGACCATCATGCTTAAGACCTTGGGATTGACCCATCTGAT
GGCCCAGTCTGGTTTGCCTATCTTGGCTGATGAGGGCAGTCGGGTAGCTATCTTCAAAGAAATTTTTGCGGATATTGGGG
ATGAACAGTCGATTGAGCAGAGTTTATCAACCTTCTCCAGTCACATGACCCACACGGTGGAAATTTTAAGAGCAGCTGAT
CAAGATTCTCTCATTCTATTTGACGAGTTGGGAGCTGGGACAGATCCGCAGGAGGGTGCGTCGCTGGCAATGGCTATTTT
GGATGACCTTCGTCTGCGGGGGATCAAGACCATGGCGACCACCCACTACCCTGAGCTTAAGGCCTACGGGATAGAAACCT
CTGGTATTGAAAATGCCAGCATGGAGTTTGATAGCAATAGCCTGCGTCCGACCTATAAGTTTATGCAGGGTGTTCCTGGT
CGCTCCAATGCCTTTGAAATTGCCCGCCGTCTGGGTCTATCTGACATCATTATCCAGTCGGCTCAGTCTTGGACCGATAC
AGATAGCGATGTGAACCGCATTATCGAGAAATTGGAAAGTCAGACGGTTGAAAGTCGTCAGCGTCTGGATAAGATTCGTG
ATGTAGAGCAAGAAAATTACAAGATGAACCGAGCCCTCCGCAAGCTCTATGACGAGCTCAATCGTGAGAGAGAAAATGAG
CTCAACAAGGCACGCTTGGAGGCCAAGGAAATTGTAGATATGGCATTGGCAGAAAGCGAGGATATTCTCAAAAATCTCCA
TGCTGCAGCTAGTCTTAAGCCCCACCAGATTATTGAAGCCAAGGCAGAGCTGAAAAAGTTGGCGCCTGAAGTGGTGGATC
TGTCTAAAAACAAGGTTCTGAAGAAAGCTAAAATTCAGAGGGAAGCCAAGGTGGGTGATGACATTATCGTTACAGCTTAT
GGACAACGTGGGACCTTGACCAATCAGCTCAAGGACGGGCGTTGGGAAGCTCAGGTTGGCTTGATTAAGATGACCTTGGC
CAAAGATGAGTTTGAGTTAGTCAAGGCGGAAAAGGCAGAGCAGCCTAAGAAACGCCAGGTTCACACAGTCAAACGTGCCA
ATGTACGAGGACCAAAAGCCCGCTTAGATCTCCGTGGCAAACGCTACGAAGAGGCTATGATGGAACTGGATGAATTTATC
GACCAGGCCCTTCTCAATAACCTAGCACAAGTAGACATTGTCCACGGTATAGGTACAGGTGTCATCCGAGAAGGGGTGAC
CAAGTACCTACGCCGAAACAAGCAGGTCAAGGAGTTCGGCTATGCCCCACAAAATGCAGGTGGATCAGGCTGTACTATTG
TGATGTTTAAGTAG

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)

MutS domain V (MutS_V)

(324-504)

Smr domain (Smr)

(702-777)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.773

100

0.405