Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Q2K21_RS21720 Genome accession   NZ_CP134053
Coordinates   5004620..5005282 (+) Length   220 a.a.
NCBI ID   WP_310773533.1    Uniprot ID   A0ABV7SPC7
Organism   Streptomyces sp. CGMCC 4.7035     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4999620..5010282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q2K21_RS21695 (Q2K21_21695) mug 5000626..5001171 (+) 546 WP_310781156.1 G/U mismatch-specific DNA glycosylase -
  Q2K21_RS21700 (Q2K21_21700) - 5001181..5001624 (-) 444 WP_310773525.1 hypothetical protein -
  Q2K21_RS21705 (Q2K21_21705) - 5001681..5002403 (-) 723 WP_310773527.1 ABC transporter permease -
  Q2K21_RS21710 (Q2K21_21710) - 5002407..5003336 (-) 930 WP_310773529.1 ATP-binding cassette domain-containing protein -
  Q2K21_RS21715 (Q2K21_21715) - 5003445..5004605 (+) 1161 WP_310773532.1 histidine kinase -
  Q2K21_RS21720 (Q2K21_21720) vraR 5004620..5005282 (+) 663 WP_310773533.1 response regulator transcription factor Regulator
  Q2K21_RS21725 (Q2K21_21725) - 5005370..5006527 (+) 1158 WP_310781158.1 ROK family transcriptional regulator -
  Q2K21_RS21730 (Q2K21_21730) - 5006880..5007641 (-) 762 WP_310773534.1 GntR family transcriptional regulator -
  Q2K21_RS21735 (Q2K21_21735) - 5007929..5008813 (-) 885 WP_310773535.1 RNA polymerase sigma-70 factor -
  Q2K21_RS21740 (Q2K21_21740) - 5009003..5009830 (+) 828 WP_310773536.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23343.91 Da        Isoelectric Point: 4.8419

>NTDB_id=802023 Q2K21_RS21720 WP_310773533.1 5004620..5005282(+) (vraR) [Streptomyces sp. CGMCC 4.7035]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLMDGIAATRAVLRTVDAPPKI
VVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPASVRQLAAAYGDNGGNRAARAAMERAALTER
EEEVLRLMTRGLSNAEIAGQLVVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=802023 Q2K21_RS21720 WP_310773533.1 5004620..5005282(+) (vraR) [Streptomyces sp. CGMCC 4.7035]
ATGCCGGTCACCGTCCTGCTCGTAGACGACGAACCCCTGGTCCGCGCGGGTCTGCGCGCCGTCCTTGAGGCGCAGCCCGA
CATCGAGGTCGTCGGGGAGGCGGCGGACGGCGCGGCGGTGATCCCGCTGGTGCGGCAACTGCGGCCGGACGTCGTCGCCA
TGGACGTGCGTATGCCTTTGATGGACGGTATCGCCGCCACGCGCGCGGTGCTGCGGACGGTCGACGCGCCACCGAAGATC
GTCGTGGTGACGACGTTCGAGAACGATGAGTACGTCTACGAGGCGCTGCGCGCGGGTGCGGACGGTTTTCTGCTGAAGCG
GGCGCGGCCGGCCGAGATCGTGCACGCGGTGCGCTTGGTCGCCGAGGGCGAGTCGTTGCTGTTCCCTGCGTCCGTACGGC
AGTTGGCCGCGGCGTACGGGGACAACGGCGGCAACCGTGCGGCCCGGGCCGCGATGGAGCGGGCCGCACTGACCGAGCGC
GAGGAGGAGGTGCTGCGGCTGATGACGCGCGGTCTGTCGAACGCGGAGATCGCCGGACAGTTGGTCGTCGGCACGGAGAC
CGTGAAGTCGCACGTCAGCGCCGTACTGGCGAAGCTGGGGGCGCGGGACCGGACACAGGCGGTGATCGCCGCGTACGAGT
CGGGGTTCGTCGCACCGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.826

99.091

0.405