Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   Q3101_RS18755 Genome accession   NZ_CP133215
Coordinates   4078286..4079410 (-) Length   374 a.a.
NCBI ID   WP_064729139.1    Uniprot ID   A0A191V189
Organism   Streptomyces sp. VNUA74     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4073286..4084410
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q3101_RS18735 (Q3101_18735) - 4074206..4075897 (+) 1692 WP_308883878.1 histidine kinase -
  Q3101_RS18740 (Q3101_18740) - 4075894..4076559 (+) 666 WP_226487421.1 response regulator transcription factor -
  Q3101_RS18745 (Q3101_18745) - 4076564..4077208 (-) 645 WP_226487422.1 phosphatase PAP2 family protein -
  Q3101_RS18750 (Q3101_18750) - 4077383..4078261 (+) 879 WP_308883879.1 hypothetical protein -
  Q3101_RS18755 (Q3101_18755) disA 4078286..4079410 (-) 1125 WP_064729139.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  Q3101_RS18760 (Q3101_18760) radA 4079492..4080901 (-) 1410 WP_064729140.1 DNA repair protein RadA Machinery gene
  Q3101_RS18765 (Q3101_18765) - 4081424..4083187 (+) 1764 WP_308883880.1 hypothetical protein -
  Q3101_RS18770 (Q3101_18770) - 4083234..4084046 (-) 813 WP_161341941.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40071.88 Da        Isoelectric Point: 5.0058

>NTDB_id=798766 Q3101_RS18755 WP_064729139.1 4078286..4079410(-) (disA) [Streptomyces sp. VNUA74]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTLLRDGLERVLRGNTGGLMVLGSDKTVEAMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=798766 Q3101_RS18755 WP_064729139.1 4078286..4079410(-) (disA) [Streptomyces sp. VNUA74]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCGCT
GAGCGCCGTGGCGCCCGGCACCCTGCTGCGGGACGGCCTGGAACGGGTCCTTCGCGGCAACACCGGCGGTCTCATGGTGC
TGGGGTCGGACAAGACCGTCGAGGCGATGTGCACGGGCGGCTTCGTGCTGGACGTCGAGTTCACGGCGACCCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTCTCCTCGGACCTGTCGAAGATCCTGCGGGCGGGTGTGCAGCTGCTGCC
CGACCCGACCATTCCGACCGAGGAGACCGGCACCCGGCACCGTACGGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TCGTGTCCGTTTCGCAGTCCATGCGGCTCATCGCCCTCTATGTCGACGGGCAGCGGCGCGTCCTGGAGGACTCCGCGGCG
ATCCTGTCCCGGGCCAACCAGGCGCTGGCCACCCTGGAGCGCTACAAGCTCCGGCTCGACGAGGTCGCCGGCACGCTCTC
CGCGCTGGAGATCGAGGATCTGGTGACCGTCCGGGACGTGTCGGCGGTCGCGCAGCGGCTGGAGATGGTGCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTCGAGCTGGGGACGGACGGGCGGCTGCTCGCGCTCCAGCTGGACGAGCTGATCGCC
GGCGTGGAGCCCGAACGCGAGCTGGTCGTGCGGGACTACGTGCCCGAGCCGACCGCCAAGCGGTCCCGTACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCACGCCGAGCTGCTCGAACTGTCCACGGTGGCCCGGGCGCTGGGTTACACCG
GGTCCCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGCGCC
ATCATCGACCGCCTCGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCGCGGGCCCGCAGCGTGCGCGAGGGGCTGTCGCGGCTCGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A191V189

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.983

96.524

0.444