Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PXX05_RS09725 Genome accession   NZ_CP119078
Coordinates   2284299..2284958 (-) Length   219 a.a.
NCBI ID   WP_275088033.1    Uniprot ID   -
Organism   Legionella cardiaca strain H63     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2279299..2289958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PXX05_RS09710 (PXX05_09710) - 2280920..2281459 (-) 540 WP_275088030.1 endopeptidase IV -
  PXX05_RS09715 (PXX05_09715) - 2281468..2282187 (-) 720 WP_275088031.1 L,D-transpeptidase -
  PXX05_RS09720 (PXX05_09720) uvrC 2282367..2284211 (-) 1845 WP_420844581.1 excinuclease ABC subunit UvrC -
  PXX05_RS09725 (PXX05_09725) letA 2284299..2284958 (-) 660 WP_275088033.1 two-component system response regulator LetA Regulator
  PXX05_RS09730 (PXX05_09730) phhA 2285191..2286009 (-) 819 WP_275088034.1 phenylalanine 4-monooxygenase -
  PXX05_RS09735 (PXX05_09735) bioC 2286140..2287012 (-) 873 WP_275090491.1 malonyl-ACP O-methyltransferase BioC -
  PXX05_RS09740 (PXX05_09740) comFC 2287052..2287750 (+) 699 WP_275088035.1 ComF family protein Machinery gene
  PXX05_RS09745 (PXX05_09745) - 2287768..2288838 (-) 1071 WP_275088036.1 M50 family metallopeptidase -
  PXX05_RS09750 (PXX05_09750) - 2288851..2289126 (-) 276 WP_275088037.1 hypothetical protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24501.69 Da        Isoelectric Point: 5.4134

>NTDB_id=797547 PXX05_RS09725 WP_275088033.1 2284299..2284958(-) (letA) [Legionella cardiaca strain H63]
MIKVLIVDDHALVRMGIRRLLEDLPDVEVVADAESGELALALVKSHKPDVVLLDMKMPGIDGWEVTRRLKKSNPQVKVIA
VTAMCTEPMPTRVLQLGAMGYLTKESGAEEMAAAIRKVARGEKYLSAEIAQKMAISSLEATQESPFDLLSEREMQVMLMI
TSGMTVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTFLAMKHRVIEQPNDALHDE

Nucleotide


Download         Length: 660 bp        

>NTDB_id=797547 PXX05_RS09725 WP_275088033.1 2284299..2284958(-) (letA) [Legionella cardiaca strain H63]
TTGATAAAAGTTCTAATTGTTGATGACCATGCCCTGGTAAGAATGGGTATTCGACGATTACTTGAGGATCTGCCTGATGT
AGAGGTAGTAGCGGATGCAGAAAGTGGTGAGCTTGCTTTGGCATTGGTAAAATCTCACAAACCCGATGTGGTATTGCTCG
ACATGAAAATGCCGGGAATTGACGGCTGGGAAGTGACAAGGCGTCTTAAAAAATCTAATCCTCAGGTTAAGGTAATTGCG
GTAACAGCGATGTGTACCGAACCAATGCCTACCCGTGTTTTACAATTAGGCGCAATGGGCTACTTGACGAAAGAATCAGG
TGCTGAGGAAATGGCCGCAGCTATTCGCAAAGTAGCCCGCGGTGAAAAATATTTAAGCGCTGAAATTGCTCAGAAGATGG
CAATTAGCAGCCTGGAAGCCACTCAAGAATCTCCTTTTGATTTGTTATCTGAGCGTGAAATGCAGGTTATGTTGATGATT
ACCAGCGGTATGACAGTTCAGGATATAGCAGATCGATTGTTTTTAAGCTCTAAAACTATTAATGGTTACCGTTATAGAAT
GTTCGAAAAACTGGGAATAAAGAATGATGTAGAGCTTACTTTCTTGGCAATGAAGCATCGTGTTATTGAACAGCCTAACG
ATGCATTGCATGACGAGTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-203)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

87.215

100

0.872
  letA Legionella pneumophila strain ERS1305867

87.215

100

0.872