Detailed information
Bioinformatically predicted
Overview
| Name | pilA | Type | Machinery gene |
| Locus tag | HIY_RS04125 | Genome accession | NZ_AP022867 |
| Coordinates | 786732..787181 (+) | Length | 149 a.a. |
| NCBI ID | WP_005656280.1 | Uniprot ID | A0A0H3PDQ7 |
| Organism | Haemophilus influenzae strain 2018-Y40 | ||
| Function | type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 781732..792181
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HIY_RS04105 (HIY_07920) | rsmE | 782198..782935 (-) | 738 | WP_005656289.1 | 16S rRNA (uracil(1498)-N(3))-methyltransferase | - |
| HIY_RS04110 (HIY_07930) | lnt | 782985..784514 (-) | 1530 | WP_079997635.1 | apolipoprotein N-acyltransferase | - |
| HIY_RS04115 (HIY_07940) | corC | 784537..785436 (-) | 900 | WP_005656283.1 | CNNM family magnesium/cobalt transport protein CorC | - |
| HIY_RS04120 (HIY_07950) | ampD | 786057..786617 (-) | 561 | WP_005648974.1 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | - |
| HIY_RS04125 (HIY_07960) | pilA | 786732..787181 (+) | 450 | WP_005656280.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | Machinery gene |
| HIY_RS04130 (HIY_07970) | pilB | 787178..788572 (+) | 1395 | WP_005656265.1 | GspE/PulE family protein | Machinery gene |
| HIY_RS04135 (HIY_07980) | pilC | 788569..789789 (+) | 1221 | WP_005656262.1 | type II secretion system F family protein | Machinery gene |
| HIY_RS04140 (HIY_07990) | pilD | 789786..790478 (+) | 693 | WP_005656260.1 | A24 family peptidase | Machinery gene |
| HIY_RS04145 (HIY_08000) | rho | 790532..791794 (-) | 1263 | WP_005648966.1 | transcription termination factor Rho | - |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 15684.12 Da Isoelectric Point: 9.3906
>NTDB_id=79566 HIY_RS04125 WP_005656280.1 786732..787181(+) (pilA) [Haemophilus influenzae strain 2018-Y40]
MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKASVSELLQASAPYKADVELCVYSTNETTNCTGGKNGIA
ADITTAKGYVASVKTQSGGITVKGNGTLANMEYILQAKGNATAGVTWTTTCKGTDASLFPANFCRSVTK
MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKASVSELLQASAPYKADVELCVYSTNETTNCTGGKNGIA
ADITTAKGYVASVKTQSGGITVKGNGTLANMEYILQAKGNATAGVTWTTTCKGTDASLFPANFCRSVTK
Nucleotide
Download Length: 450 bp
>NTDB_id=79566 HIY_RS04125 WP_005656280.1 786732..787181(+) (pilA) [Haemophilus influenzae strain 2018-Y40]
ATGAAATTAACAACACAGCAAACCTTGAAAAAAGGTTTTACATTAATCGAGCTAATGATTGTGATTGCAATTATTGCTAT
TTTAGCCACTATCGCAATTCCTTCTTATCAAAATTATACCAAAAAAGCTTCGGTATCCGAATTACTGCAAGCATCTGCAC
CTTATAAGGCTGATGTGGAATTATGTGTATATAGCACAAATGAAACAACAAACTGTACGGGTGGAAAAAATGGTATTGCA
GCTGATATTACAACAGCAAAAGGCTATGTAGCCTCAGTGAAAACTCAATCGGGTGGCATTACAGTAAAAGGGAATGGCAC
ATTGGCAAATATGGAATATATTTTGCAAGCTAAAGGTAATGCTACAGCAGGTGTAACTTGGACAACAACCTGCAAAGGAA
CGGATGCCTCTTTATTTCCAGCAAATTTTTGCAGAAGTGTCACAAAATGA
ATGAAATTAACAACACAGCAAACCTTGAAAAAAGGTTTTACATTAATCGAGCTAATGATTGTGATTGCAATTATTGCTAT
TTTAGCCACTATCGCAATTCCTTCTTATCAAAATTATACCAAAAAAGCTTCGGTATCCGAATTACTGCAAGCATCTGCAC
CTTATAAGGCTGATGTGGAATTATGTGTATATAGCACAAATGAAACAACAAACTGTACGGGTGGAAAAAATGGTATTGCA
GCTGATATTACAACAGCAAAAGGCTATGTAGCCTCAGTGAAAACTCAATCGGGTGGCATTACAGTAAAAGGGAATGGCAC
ATTGGCAAATATGGAATATATTTTGCAAGCTAAAGGTAATGCTACAGCAGGTGTAACTTGGACAACAACCTGCAAAGGAA
CGGATGCCTCTTTATTTCCAGCAAATTTTTGCAGAAGTGTCACAAAATGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilA | Haemophilus influenzae Rd KW20 |
95.302 |
100 |
0.953 |
| pilA | Haemophilus influenzae 86-028NP |
91.946 |
100 |
0.919 |
| pilA | Glaesserella parasuis strain SC1401 |
54.054 |
99.329 |
0.537 |
| pilA2 | Legionella pneumophila strain ERS1305867 |
40.667 |
100 |
0.409 |
| pilA2 | Legionella pneumophila str. Paris |
40.845 |
95.302 |
0.389 |
| pilA | Vibrio campbellii strain DS40M4 |
40.426 |
94.631 |
0.383 |